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Antibiotic Prophylaxis Prior to Dental Procedures in Patients With Orthopedic ImplantsLingering historical concerns have led to inconsistent practices in antibiotic prophylaxis in this population.
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Another Adverse Effect of the Opioid Epidemic: Hepatitis C InfectionsAn increase in injection drug use in the United States has augmented the likelihood of acquiring HCV, particularly genotype 3.
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The C Diff Foundation Raises Clostridium difficile Infection (C difficile) Clinical Trial Awareness WorldwideIn the USA: Nearly half a million Americans suffer from Clostridium difficile (C. diff.) infections in a single year according to a study released in 2015 by the Centers for Disease Control and Prevention.
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High-Resistance Therapy Options for Treatment-Naïve Patients With HIVJoseph Eron, MD, Daniel R. Kuritzkes, MD, and Monica Gandhi, MD, MPH, discuss the likelihood of other combination regimens for the treatment of multidrug-resistant HIV, including monoclonal antibodies.
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It doesn’t get much beta than this: Novel beta-lactam antibiotics for multidrug-resistant gram-negative organismsAs the threat of infection with multidrug-resistant gram-negative organisms persists, new antimicrobials are a welcome addition to the armamentarium of infectious diseases clinicians.
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DTG/3TC Offers Dual-Drug Therapy for Initial HIV TreatmentFor the first time, patients with new HIV diagnoses have a 2-drug regimen option.
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What's on Your Antimicrobial Stewardship "Wish List"?If resources and funds were unlimited, what would the ideal stewardship program look like?
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An Unknown Contagious Rash: Case Report and Literature Review of Norwegian Crusted ScabiesA patient with HIV and skin lesions should trigger a broad differential.
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Employee Health After the COVID-19 Pandemic: Stronger Than YesterdayFor providers on the front lines, lessons learned can help inform strategies to enhance the protection of their health going forward.
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Gender-Affirming Care in Persons Living With HIVGender-affirming hormone therapy (GAHT) therapy consists of administration of exogenous hormones and suppression of endogenous hormone production, with the goal of obtaining characteristics more congruent with an individual’s gender identity. Here is a review of these therapies and consideration for PrEP and the risks associated with HIV in this diverse population.
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A Penicillin Allergy Questionnaire for Outpatient ClinicsClinicians developed an algorithm and screening questionnaire for outpatient penicillin allergy evaluation, designed to stratify patients into high- and low-risk penicillin allergy groups. Here is the sample questionnaire to consider for use in clinics.
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A Peculiar Finding in an Unfamiliar PatientA rare metallo-ß-lactamase makes its way into the United States via an 84-year-old patient.
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Summarizing SGLT-2 Inhibitor Usage in People With Diabetes and HIVIn persons living with HIV and diabetes, the management of diabetes is lagging behind the evidence. Despite SGLT-2 inhibitors demonstrating robust clinical data in the general population, they are grossly underused in persons with HIV and diabetes.
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Can We Beat SARS-CoV-2? Lessons From Other CoronavirusesA scientist who focuses on engineering bacteriophages for use as therapeutics shares thoughts on SARS-CoV-2.
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The Case of Late Aspergillus Fumigatus Infection of Implantable Cardioverter Defibrillator LeadsQuick action was needed against this very rare cause of fungal endocarditis.
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New Initiatives for HIV Taking Off This YearAdvances in antiretroviral therapies increase opportunities for patients with HIV to have more successful treatment outcomes.
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Final Diagnosis: Disseminated Kaposi Sarcoma With Tonsillar and Pulmonary InvolvementA shocking find on a CT scan leads to an unexpected diagnosis.
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Get Off the SOFA! Introducing the Quick Pitt Bacteremia ScoreThe quick Pitt Bacteremia Score offers accuracy comparable to the original version's across multiple infections, and maintains ease of use.
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Aging Individuals With HIV Should Be Closely Monitored for DiabetesAlthough antiretroviral therapy has led to significantly longer life expectancies among individuals with HIV, this, in turn, has contributed to the likelihood that these individuals will develop age-related comorbidities at earlier ages.
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Two More Agents Bolster the Arsenal Against Gram-Negative ResistanceAs the antibiotic pipeline produces new therapies, clinicians must understand each agent’s specific role in manage­ment of patients infected by multidrug-resistant pathogens.
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Risks Associated With Direct-Acting Antivirals—Smoke or Fire?Should clinicians be extra vigilant when deciding who receives antiviral therapy, or are the adverse effects few and infrequent?
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Is Investment in New Technologies for Diagnosing Schistosomiasis Justified in an Era of Schistosoma Elimination?The emergence of new species creates pressure for developing affordable and reliable diagnostic strategies.
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Exciting New Hepatitis C Therapies Approved at the End of 2017Treatment-experienced patients still have some good options.
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Preventing Clostridium difficile From Getting LooseWhat can healthcare providers do to stop these infections before they start?
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Intravenous Fosfomycin In Development for United StatesBecause of the recent concern in the United States around the rise of resistant pathogens, intravenous fosfomycin has gained renewed interest because of its activity and demonstrated synergy with other classes of antibiotics.
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Food Preparation Safety: Tips to Avoid Foodborne Illness During ThanksgivingWe’ve compiled a list of key food safety tips that you need to know in order to have a safe, bacteria-free holiday.
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Preliminary Negative Cultures for the De-Escalation of MRSA TherapyThis article evaluates the point in microbiological workup at which results of respiratory secretion and blood cultures could be interpreted as excluding MRSA and, thus, no longer warrant the empirical vancomycin therapy.
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The Case of Late Aspergillus Fumigatus Infection of Implantable Cardioverter Defibrillator LeadsQuick action was needed against this very rare cause of fungal endocarditis.
