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Cognitive Disorders are a Risk Factor for Severe COVID-19Alzheimer’s disease, dementia, and genetic variations in areas key to viral infection are risk factors for severe COVID-19 a new study suggests.
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Cryptosporidium: A Potentially Fatal Cause of Diarrhea in a Heart Transplant RecipientExpanding the differential for diarrhea beyond Clostridium difficile.
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It Takes Two to TANGO With a CarbapenemaseBecause of the global rise in antimicrobial resistance, meropenem-vaborbactam, the first carbapenem/β-lactamase combina­tion medication, is a welcome new antibac­terial.
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Texas Could Be Site of Next Large Measles Outbreak, Study PredictsTexas could be the site of the next large measles outbreak in the United States, according to a new study that highlights the low vaccination rates among schools there.
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Improving Vaccine Uptake in a Cohort of Patients With AspleniaThis is one of the first studies examining the effect of a dedicated postsplenectomy comprehensive clinic.
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Implications of the 21st Century Cures Act on Antibiotic Drug DevelopmentExperts weigh in on what Congress is doing to tackle the threat of antibiotic resistance.
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COVID-19: How Temple University Hospital Is Addressing the PandemicThe health system’s response could be used as a teaching model for addressing future infectious disease threats.
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The Infectious Disease Physician's Holiday Wish ListFor all you last-minute shoppers, Payal K. Patel MD, MPH, and Sujit Suchindran MD, have put together a wish list of the top items to get the infectious disease physician in your life.
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Women Living With HIV and Menopause: Bridging the Data GapWomen living with HIV are at elevated risk for comorbidities as their life expectancy increases.
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"Antibiotic Never Events": The Ideal Target to Reduce Antimicrobial ExposureBy stopping unnecessary antibiotics before they start, clinicians can avoid unnecessary harm to the patient and the population.
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With the Opioid Epidemic, Communities See Dramatic Increases in Infectious DiseasesRising incidence of viral and bacterial infections has accompanied the opioid crisis, but it also presents new opportunities for multidisciplinary treatment and preventive care.
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Antibiotic Prophylaxis Prior to Dental Procedures in Patients With Orthopedic ImplantsLingering historical concerns have led to inconsistent practices in antibiotic prophylaxis in this population.
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Another Adverse Effect of the Opioid Epidemic: Hepatitis C InfectionsAn increase in injection drug use in the United States has augmented the likelihood of acquiring HCV, particularly genotype 3.
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The C Diff Foundation Raises Clostridium difficile Infection (C difficile) Clinical Trial Awareness WorldwideIn the USA: Nearly half a million Americans suffer from Clostridium difficile (C. diff.) infections in a single year according to a study released in 2015 by the Centers for Disease Control and Prevention.
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High-Resistance Therapy Options for Treatment-Naïve Patients With HIVJoseph Eron, MD, Daniel R. Kuritzkes, MD, and Monica Gandhi, MD, MPH, discuss the likelihood of other combination regimens for the treatment of multidrug-resistant HIV, including monoclonal antibodies.
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It doesn’t get much beta than this: Novel beta-lactam antibiotics for multidrug-resistant gram-negative organismsAs the threat of infection with multidrug-resistant gram-negative organisms persists, new antimicrobials are a welcome addition to the armamentarium of infectious diseases clinicians.
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DTG/3TC Offers Dual-Drug Therapy for Initial HIV TreatmentFor the first time, patients with new HIV diagnoses have a 2-drug regimen option.
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What's on Your Antimicrobial Stewardship "Wish List"?If resources and funds were unlimited, what would the ideal stewardship program look like?
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An Unknown Contagious Rash: Case Report and Literature Review of Norwegian Crusted ScabiesA patient with HIV and skin lesions should trigger a broad differential.
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Employee Health After the COVID-19 Pandemic: Stronger Than YesterdayFor providers on the front lines, lessons learned can help inform strategies to enhance the protection of their health going forward.
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Gender-Affirming Care in Persons Living With HIVGender-affirming hormone therapy (GAHT) therapy consists of administration of exogenous hormones and suppression of endogenous hormone production, with the goal of obtaining characteristics more congruent with an individual’s gender identity. Here is a review of these therapies and consideration for PrEP and the risks associated with HIV in this diverse population.
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A Penicillin Allergy Questionnaire for Outpatient ClinicsClinicians developed an algorithm and screening questionnaire for outpatient penicillin allergy evaluation, designed to stratify patients into high- and low-risk penicillin allergy groups. Here is the sample questionnaire to consider for use in clinics.
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A Peculiar Finding in an Unfamiliar PatientA rare metallo-ß-lactamase makes its way into the United States via an 84-year-old patient.
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Summarizing SGLT-2 Inhibitor Usage in People With Diabetes and HIVIn persons living with HIV and diabetes, the management of diabetes is lagging behind the evidence. Despite SGLT-2 inhibitors demonstrating robust clinical data in the general population, they are grossly underused in persons with HIV and diabetes.
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Can We Beat SARS-CoV-2? Lessons From Other CoronavirusesA scientist who focuses on engineering bacteriophages for use as therapeutics shares thoughts on SARS-CoV-2.
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The Case of Late Aspergillus Fumigatus Infection of Implantable Cardioverter Defibrillator LeadsQuick action was needed against this very rare cause of fungal endocarditis.
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New Initiatives for HIV Taking Off This YearAdvances in antiretroviral therapies increase opportunities for patients with HIV to have more successful treatment outcomes.
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Final Diagnosis: Disseminated Kaposi Sarcoma With Tonsillar and Pulmonary InvolvementA shocking find on a CT scan leads to an unexpected diagnosis.
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Get Off the SOFA! Introducing the Quick Pitt Bacteremia ScoreThe quick Pitt Bacteremia Score offers accuracy comparable to the original version's across multiple infections, and maintains ease of use.
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Aging Individuals With HIV Should Be Closely Monitored for DiabetesAlthough antiretroviral therapy has led to significantly longer life expectancies among individuals with HIV, this, in turn, has contributed to the likelihood that these individuals will develop age-related comorbidities at earlier ages.
