Infectious Disease Update: This Week's Top Stories
Read and watch the infectious disease trial data shared this week.
Moderna Omicron-Targeting Booster Candidates Demonstrate Superiority Over its Spikevax Booster
Safety profile in this study showed the frequency of adverse reactions with these boosters were similar or lower than that of either a second or third dose of the original vaccine.
This Week in Infectious Disease: The Top 5 Articles
Looking for the latest developments in infectious disease? Here are the top stories Contagion covered this week.
How Did Lifting School Mask Mandates Affect COVID-19 Infections?
In Boston school districts, lifting mask mandates was correlated with an additional 44.9 COVID-19 infections per 1000 students and staffers.
Wearing Masks Didn’t Increase Face Touching Among Kids in Simulated School Study
The benefits to children of wearing face masks to prevent COVID-19 outweigh potential infectious risks from face touching, according to a study analyzing hand-to-face contact in a simulated school environment.
Phase 3 Trial of Vaxxinity’s COVID-19 Vaccine as a Heterologous Booster Advances
Vaxxinity is moving forward with research to bring its UB-612 COVID-19 vaccine to market as a mix-and-match booster to authorized vaccines.
COVID-19 Vaccine Boosters: Roadblocks, the Future, and Communicating the Benefits to Patients
“In the long run, what we will have is a virus that will become endemic in
our population," said Donald J. Alcendor, MD. "The idea of thinking we can chase variants with boosters is a failed effort. We must realize that.”
Long COVID Symptoms in 6% of People with Symptomatic Infection
Nearly 150 million people were affected by common symptoms of long COVID in 2020 and 2021, according to an analysis of global data on more than 1.2 million people.
Long-COVID: How Common Is It?
The simple truth is that the long-lasting symptoms of COVID are something we should all be worried about.
Who Doesn’t Love a Prequel? SARS Before CoV-2
Our cover story for the October 2022 print edition of Contagion details the original coronavirus.
“Diagnostic Stewardship Is Always an Area of Need”
At IDWeek 2022, Erica Stohs, MD, MPH, presented surprising findings about unnecessary antibiotics in a cohort coinfected with COVID-19 and pneumonia.
SNG001 Fails Primary Endpoints, But May Alleviate Long COVID Symptoms
Despite no significant reduction in time to discharge or recovery, inhalable SNG001 may lessen common symptoms of “long COVID.”
Time to COVID-19 Breakthrough Infection After Full Vaccination
Breakthrough COVID-19 infections were rare in fully vaccinated individuals, but the average breakthrough occurred just under 50 days after complete vaccination.
Novavax Recommended as Mix-and-Match Booster Dose After Primary COVID-19 Vaccine Series
The Novavax booster dose administered in a small study induced more robust antibody responses and its safety profile was considered favorable.
COVID-19 Vaccination Protects Against Severe Clinical Outcomes in Hospitalized Adults
Overall, 91.5% of the hospitalized adults with COVID-19 were unvaccinated and 8.5% of patients were fully vaccinated.
Historical Perspective: Lessons from SARS-CoV-1
Before the emergence of COVID-19, this precursor virus was a global concern.
The Top Infectious Disease Stories This Week
Articles covering respiratory infections were our most-clicked this week.
Moderna’s Bivalent COVID-19 Booster Elicits Superior Antibody Responses
Moderna’s new bivalent COVID-19 booster, which includes 25 micrograms each of messenger RNAs from the Wuhan-Hu-1 and Omicron B.1.1.529 variants of SARS-CoV-2, elicited antibody responses that were superior to those elicited by the original vaccine.
Pfizer-BioNTech Releases Early Results from Bivalent Booster Vaccine Trial
Preliminary results from a phase 2/3 trial suggest Pfizer-BioNTech’s Omicron BA.4/BA.5 bivalent COVID-19 booster vaccine provides better protection for younger and older adults.
Increase in Enteroviruses Seen with Decreases in COVID-19 Precautions
The Centers for Disease Control and Prevention (CDC) reports the rise in pediatric acute respiratory illnesses especially as there is a decrease in hygiene measures that were previously employed during the pandemic.
FDA Authorizes mRNA Bivalent Boosters for Younger Pediatric Groups
The Moderna vaccine can be administered to children as young as six years old and the Pfizer-BioNTech vaccine for kids as young as five years old.
COVID-19 Vaccines, Boosters and Prior Infection Significantly Reduce Risks
A comprehensive cohort study of COVID-19 data has reinforced the effectiveness of the various vaccines, boosters, and prior infection in protecting against infection, hospitalization and death.
COVID-19 Hospitalizations Broken Down by Vaccination Status
A recent study broke down hospitalizations associated with COVID-19 in adults between January 2021 and April of this year, based upon vaccination status.
This Week's Most-Clicked Infectious Disease Stories
These were our most popular articles this week. Catch up with these trending infectious disease stories.
Health Officials Urge Flu Vaccination, But Few Adults Plan to Get the Shot
The CDC is urging all eligible persons to receive a flu shot, but a new survey shows fewer adults are planning to get the vaccine this season.
September's Top 5 Infectious Disease Stories
Catch up on Contagion's top stories from the month of September.
Shionogi Reaches Endpoint for Phase 3 COVID-19 Pill
The investigational therapy demonstrated time to first resolution of the five COVID-19 symptoms was significantly reduced in those treated with low dose of medication.
Bivalent SARS-CoV-2 Vaccine Might Offer Better Omicron Protection
Interim data show a bivalent vaccine that contains the Omicron variant may be more effective.
Pfizer-BioNTech, Moderna Seek FDA EUA for Bivalent Vaccine Boosters in Pediatric Population
These vaccines target the wild strain as well as the Omicron BA.4/BA.5 variants.
Assessing Excess Mortality from COVID-19 Across US States
Investigators examined all-cause excess mortality and sought to uncouple it from COVID-19 in US states with high vaccination rates.
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