SPOTLIGHT -
COVID-19 Antibody Levels Rise Higher, Fall Faster in Children
Durable immune responses are seen in all age groups, even with significant discrepancies in antibody levels between children and adults.
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Risk of Maternal Morbidity Differs by COVID-19 Variant
Risk of severe maternal morbidity was highest during the period when Delta was the predominant COVID-19 variant.
Novavax Seeks FDA Authorization for its COVID-19 Vaccine as Booster
If it is granted an Emergency Use Authorization (EUA), the vaccine could be used as a booster dose for individuals 18 years and older vaccinated with any of the other available COVID-19 vaccines.
Reinfection, Vaccination, and Post-Recovery Shots
Investigators sought to address the effectiveness of vaccination after COVID-19 recovery.
Health Care Utilization in the Months After COVID-19 Infection
6 months after acute COVID-19 infection, patients had elevated usage of health care services to treat post-COVID conditions.
United Kingdom Authorizes Moderna Bivalent Booster COVID-19 Vaccine
The booster is designed for immunization against the original wild strain as well as Omicron variant.
Omicron BA.4 and BA.5 Can’t Be Neutralized by Prior Infection
Neutralization of BA.4 and BA.5 dropped significantly for individuals who were infected with a previous strain of Omicron, even if they were also vaccinated.
New CDC Guidelines Reduce Quarantine After COVID-19 Exposure
Asymptomatic individuals in low-risk settings do not have to quarantine after COVID-19 exposure, CDC says.
BioNTech Says Variant COVID-19 Vaccines May Be Available as Early as October
The company and its partner, Pfizer, are preparing for the potential launch of 2 variant-adapted bivalent COVID-19 vaccines assuming authorizations from FDA and EMA.
Top 5 Infectious Disease Stories of the Week: August 5, 2022
Questionnaire Results Show 1 in 8 are Developing Long COVID
The findings come from a large Dutch study and demonstrate the symptoms of the virus months after people's acute infections.
Novavax Begins COVID-19 Vaccine Trial for Children 6 Months Through 11 Years
This study looks to identify safety, efficacy of the vaccine in the youngest pediatric populations.
Infectious Disease Virologist: “Nobody Should be Scared of Paxlovid Rebound”
The benefits outweigh the possible rebound of symptoms, according to an investigator who studied the antiviral.
Pfizer-BioNTech Begin Study Looking at Enhanced COVID-19 Vaccine
The modified spike protein in this next-generation bivalent candidate is part of the companies' strategy to try and provide vaccines with longer and more durable protection against the virus.
The Case for Variant-Specific Boosters
Omicron-specific vaccine boosters are coming, but just how necessary are they?
Longer Interval Between COVID-19 Vaccine Doses May Cut Risk of Myocarditis or Pericarditis
The highest rate of myocarditis or pericarditis after mRNA COVID-19 vaccination occurred among young men ages 18 to 24 after receiving a second dose of the Moderna vaccine.
Regular COVID-19 Screening in Schools Can Control Infections, Limit Closures
The model suggests screening unvaccinated students could reduce absences by 80% compared to reactively closing classes with infected students.
COVID-19 Vaccine Boosters: Benefits, Expansion of Eligibility, and Mixing and Matching of Vaccines
Clinicians offer insights on a variety of elements surrounding boosters.
Full COVID-19 Vaccination Cuts Reinfection Risk in Half
Prior infection is not enough: COVID-19 vaccination reduces the risk of reinfection by 50%.
A Day in the Life of a Public Health Professional
As the pandemic enters its third year, fatigue and frustration grow, but there is hope for the future.
COVID-19 Antibodies After 1 and 2 Pfizer Vaccine Boosters
This Israeli study found 3 and 4 doses of Pfizer-BioNTech bolstered antibody titers in adults 60 and older.
President Biden Tests Positive for COVID-19
He is experiencing mild symptoms and is going to take Paxlovid.
CDC Director: Recommends Authorization for Novavax COVID-19 Vaccine
This decision follows votes to allow the vaccine to be indicated for prevention of the virus in adults 18 years and older.
WHO and UNICEF: Global Childhood Vaccine Coverage Declined Last Year
A specific immunization marker showed the percentage of children receiving common vaccines fell 5% between 2019 and 2021.
Tracking the Mutations of the Latest Omicron Variants
The BA.2 COVID-19 variant maintained the mutations necessary for viral entry, but developed an increased ability to evade neutralization by monoclonal antibodies.
Report: COVID-19 Had Dramatic Effect on Life Expectancies of Poor and Minorities
Though all racial and ethnic groups saw declines in life expectancy, the impact was greater among members of minority groups.
Pfizer Vaccine Efficacy Against Omicron in Children 5-11 Years
In children 5-11 years old, 2 doses of the Pfizer-BioNTech COVID-19 vaccine were moderately effective against documented, symptomatic Omicron infection.
The Best Time to Get a Booster to Prevent COVID-19 Reinfection, Breakthrough Infection
Predicted time to breakthrough infection after mRNA vaccination was significantly longer than the time to breakthrough infection after natural infection or after viral vector vaccination.
CDC: COVID-19 "Perfect Storm" Against Efforts to Reduce Antimicrobial Resistance
CDC attributes a 15% increase in deaths from antimicrobial-resistant infections in 2020 to impacts of COVID-19 on health and healthcare.
EMA Plans Anaphylaxis Label on Novavax COVID-19 Vaccine
The European agency says there have been “a few cases of anaphylaxis.” The label will also include warnings for paraesthesia and hypoaesthesia.