Gastrointestinal Infections

Recommendations for treating C. difficile upon a first recurrence as well as following multiple recurrences based on currently available treatment options and recommendations by the IDSA/SHEA clinical practice guidelines.

A panel of clinicians recognize the challenges associated with screening patients for the C. difficile infection and highlight factors that should prompt someone for an evaluation.

Types of testing algorithms used in clinical practice to help clarify a diagnosis of C. difficile infection.

Important things to understand about diagnosing C. difficile and recommendations for properly differentiating the condition from other diseases when working-up a patient.

A discussion regarding the increasing frequency of C. difficile recurrence and its effects on patients and the healthcare system.

Sources of transmission and challenges that impact the management of community-onset C. difficile.

What healthcare providers need to know about the 2 strains of C. difficile, including types of patients impacted and typical outcomes.

Understanding the burden of C. difficile across the United States, panelists explore common risk factors associated with the condition and discuss the different ways it can manifest in patients.

Biologics have become a novel treatment in recurrent C. difficile.

Community-acquired infections—including those associated with outpatient settings—are still problematic, authors say.

Results from England’s first licensed FMT stool bank are now available.

An electronic alert that aids in diagnostic stewardship may be helpful in reducing inappropriate testing for C diff, according to a new study.

Using enteral vancomycin for C diff prophylaxis may be the key to reducing morbidity and improving outcomes in pediatric and young adult recipients of HSCT.

Rebiotix has announced that it has completed enrollment of a phase 3 clinical trial for RBX2660.

Jab could save 600,000 lives, and hundreds of millions in health care costs.

DNA methyltransferase, an epigenetic process, has been found to mediate sporulation and pathogenesis in C diff.

Intravenous treatment of acute gastroenteritis can be costly and uncomfortable. A phase 3 clinical trial showed positive results for a bimodal release oral ondansetron tablet, finding the drug effective in treating nausea and vomiting.

RHB-105 (Talicia) is the only rifabutin-based therapy approved for the treatment of H pylori infection and is designed to address the high resistance of H pylori bacteria to current clarithromycin-based standard-of-care therapies.