Alleged Penicillin Allergies Lead to Higher Risk of MRSA and C difficile
Alternative agents are often broader spectrum than ß-lactams, subjecting patients to collateral damage and subsequent selection for resistant organisms and Clostridium difficile.
Changes in Recommendations for Diagnosis, Disease Severity, and Treatment of C difficile Infection in the 2017 Update to the IDSA/SHEA Clinical Practice Guidelines
The updated guidelines recommend targeting those with active infection and avoiding treatment of “carriers” of C difficile who are colonized but not symptomatic.
Multistate Outbreak of Cyclospora Connected to Pre-Packaged Vegetable Trays
The CDC and FDA are investigating a multistate outbreak of Cyclospora linked with vegetable trays produced by Del Monte Fresh Produce.
Top Infectious Disease News of the Week—June 10, 2018
Stay up-to-date on the latest infectious disease news by checking out our top 5 articles of the week.
Colistin-Resistant E coli Found in Almost All Residents of Rural Vietnam Village
Sixty-nine out of the 70 colistin-resistant isolates had either mcr-1 and/or mcr-3 genes.
Genome Sequencing Identifies Patterns in C diff Transmission and Infection
McGill University researchers find that infection with C difficile might more likely be linked to infected than colonized donors.
California Reports Over 100 Illnesses Associated with Canada's Norovirus Outbreak
The California Department of Public Health warns consumers to avoid the consumption of raw oysters harvested in British Columbia due to risk of contamination.
Recently Discovered Coronavirus Shows Potential for Cross-Species Transmission
A newly identified porcine virus has been found to be able to get into human cells in the laboratory setting.
Dry Rectal Swabs Prove Effective Alternative to Stool Samples for C. diff Diagnosis
A new study suggests that for simple PCR-based detection of C. diff, dry rectal swabs were an effective substitute to the use of stool samples.
Exploring Microbiome Changes Associated with C. diff to Prevent or Reverse Colonization
A recent review article looks at literature exploring risk factors and C. diff epidemiology to inform future preventive strategies.
Stronger Hand Hygiene & Environmental Cleaning Best Combination for Reducing C. diff
An economic evaluation finds that a bundled approach of stronger hand hygiene and improved environmental cleaning proved to be the best combination for reducing C. diff.
High Dose Oral Vancomycin Optimal Treatment Regimen for C difficile
A recent study finds high dose of oral vancomycin may be optimal treatment for C. difficile.
Eravacycline Proves Non-Inferior to Meropenem for the Treatment of cIAI in IGNITE4 Trial
Data from the IGNITE4 phase 3 trial supports the use of eravacycline for the treatment of complicated intra-abdominal infections (cIAI), including infections caused by pathogens resistant to other antibiotics.
Exploring the Best Treatment Option for Initial C. diff Infection In Pediatric Patients
Dr. Thomas Sandora shares recent data on screening for asymptomatic carriage of Clostridium difficile and provides insight into what the preferred first-line treatment for the infection in children.
Top Infectious Disease News of the Week—April 8, 2018
Microbiota-Based Therapy Shows Promise for C difficile Sufferers
One dose of microbiota-based therapy proved more effective than 2 at wiping out recurrent C. difficile infection.
Should Early FMT Be First-Line Treatment for Severe CDI?
Given the impressive efficacy of fecal microbiota transplantation (FMT) on decreasing recurrence of Clostridium difficile infection (CDI), the next logical step is seeing how it works for hospitalized patients with CDI.
Evidence-Based Intervention Reduces C. diff Rates in Adults With Cancer
SMUCLA implements high-touch wipe down intervention to address the need for environmental disinfection of cancer patient care areas.
C difficile Rates in the United Kingdom
Dr. Richard Vickers, discusses C. difficile rates in the United Kingdom.
FMT Model Predicts Which Bacterial Strains Will Engraft to Recipient
Investigators develop a statistical model predicting which bacterial strains will engraft after FMT.
Top Infectious Disease News of the Week—February 11, 2018
IDSA & SHEA Release Updated Clinical Practice Guidelines for Clostridium difficile Infection
Fecal transplantation and molecular testing are among the new recommendations.
What Are the Next Steps for Ridinilazole?
Dr. Richard Vickers, discusses what the next steps are for Summit Therapeutic’s ridinilazole.
Norovirus Outbreak Hits Winter Olympic Games
Following an outbreak of norovirus in Pyeongchang ahead of the Winter Olympics, health officials are taking steps to stem the outbreak and keep attendees healthy.
Governmental Intervention Needed to Ensure Hospital Mattresses Get Cleaned Appropriately
Edmond Hooker, MD, DrPH, stresses that the FDA and the CDC need to intervene to ensure that hospital mattresses get cleaned appropriately.
Understanding What Motivates Health Care Works Crucial to Reducing C. diff Rates
Barley Chironda, RPN, CIC, stresses that understanding what motivates health care workers’ actions is crucial for reducing C. diff rates in hospitals.
How Do C. diff-Associated Costs Compare With Other HAIs?
Glenn Tillotson, PhD, FIDSA, explains how costs associated with Clostridium difficile compare with other problematic health care-associated infections.
Top Infectious Disease News of the Week—January 28, 2018
FDA Grants 510(k) Clearance to Market 2 Campylobacter Diagnostic Tests
The FDA grants 510(k) clearance to TECHLAB to market 2 noninvasive tests intended to aid in the diagnosis of campylobacteriosis.
Immunization Coverage: Why It's Harder to Cover Adults
Richard Haupt, MD, MPH, explains why it’s harder to cover adults rather than children when it comes to vaccination.
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