Prevention

The FDA has granted EUA for the Allplex HSV-1&2/VZV/MPXV Assay (Seegene USA), the first multiplex PCR test designed to simultaneously differentiate HSV-1, HSV-2, VZV, and mpox virus from ulcerative skin lesions in a single run.

Investigational mRNA influenza vaccine prompts broader immune response than conventional vaccines, with activity against multiple strains.

Fluoroquinolones are broadly active and convenient, but black box warnings and resistance concerns have reshaped when and how clinicians should use them.

Catherine M. Stein, Evelyn Griffin, Hilary Blackburn, Kirk Milhoan, and Raymond Pollak join ACIP as the panel prepares to vote on MMRV, hepatitis B, and COVID-19 recommendations following the June reconstitution.

We’ve compiled a list of key food safety tips that you need to know in order to have a safe, bacteria-free holiday.

The lawsuit comes as the RSV market is likely to get more crowded, with a pending approval for Pfizer's pediatric indication later this month and a BLA submission from Moderna recently filed.

The vaccine targets an additional 8 unique serotypes that disproportionally affect the adult population.

Evusheld, the only FDA-approved COVID-19 pre-exposure prophylactic, is anticipated to be ineffective against the emerging XBB.1.5 variant.

Texas judge Reed O’Connor ruled that requiring employers to cover the medical expense of HIV PrEP is a violation of religious freedom.

The FDA lifted a clinical hold on investigational lenacapavir for HIV treatment and pre-exposure prophylaxis. All clinical studies evaluating injectable lenacapavir can now resume.

Dr. Simon Portsmouth of Shionogi discusses the trial results of their once-daily oral COVID-19 antiviral, S-217622, as well as the significance of the therapy as vaccine efficacy wanes in the age of Omicron.

In Germany, HIV pre-exposure prophylaxis users are recommended to receive regular HIV, STI, and renal function testing. How frequently are PrEP users getting tested?

A large surveillance study of 2 symptom-reporting databases found side effects after Moderna or Pfizer-BioNTech COVID-19 vaccination were frequently nonserious and resolved within 1-2 days.

“People don’t recognize that at least 1 in 5 of the deaths from opioids may result from endocarditis,” said National Institute of Drug Abuse (NIDA) director Dr. Nora Volkow, adding that endocarditis is “100% preventable.”

Convalescent plasma safely raised antibody levels in children at high risk of severe or fatal COVID-19, successfully neutralizing the virus but unlikely to provide lasting protection.

Two different doses of the company's mRNA vaccine were found to increase antibodies by up to 83-fold.

A novel digital pill was 98% effective in tracking daily HIV PrEP adherence.

HPV vaccination decreases cervical cancer incidence and mortality, but it is most effective in young women and girls.

New cohort data from VA medical centers provide more evidence of a correlate between antibody levels and vaccine effectiveness for mRNA vaccines.

The CDC updated its HIV PrEP guidelines, including a recommendation that doctors talk to all sexually active adults about HIV prevention and prescribe PrEP to anyone who asks for it.

Merck announced an enrollment pause in 2 of their stage 3 clinical trials for once-monthly oral islatravir for HIV PrEP. Enrolled participants will continue receiving study medicine.

Only 1 in 3 heterosexually active adults is aware of HIV PrEP, and this is even lower among Hispanic/Latinx men and women.

A new report suggests FDA and CDC deliberations may result in booster doses of the mRNA vaccine becoming available by this weekend.

The Biden administration is also setting mandates for health care workers in facilities receiving federal aid.

The ACIP considered the benefits of the newly emergency-authorized vaccine versus the risks of COVID-19 in children aged 5-11 years old.