ID Week

Helen Chu, MD, MPH, discussed the "Seattle Flu Study" with Contagion at IDWeek 2019.

Elizabeth Hirsch, PharmD, previews her piece with Mélanie Mahoney, PharmD student, on 2019 updates to CLSI breakpoints.

In the absence of interpretive criteria, Fosfomycin has been used to treat Psuedomonas aeruginosa infections, but new research suggests that this option should be evaluated further.

Millennials are a major population affected by the opioid crisis, which has now translated to an increase in hepatitis C virus infections among the generation.

Long-term care facilities participating in a statewide initiative in Nebraska saw improvements in antimicrobial stewardship, including drops in antibiotic starts and C diff infections.

Hermione Hurley, MD, MCBhB, discusses the intersection of substance use disorder and infectious disease.

A team of investigators set out to evaluate if administering CMV HIG to women with primary CMV infection during pregnancy could reduce congenital infections.

In a late-breaking presentation at IDWeek 2019, investigators from Israel sought to evaluate the effect of the antiviral drug valacyclovir on the rate of vertical transmission of CMV.

Jason Pogue, PharmD, BCPS, BCIDP, shares that SIDP will become the fifth partner in IDWeek, joining the Infectious Diseases Society of America, the HIV Medicine Association, the Pediatric Infectious Diseases Society, and the Society for Healthcare Epidemiology of America.

Machine learning prediction accuracies ranged from 75.6% (P aeruginosa and ceftazidime; 90/119 correctly predicted) to 98.1% (P aeruginosa and amikacin; 105/107 correctly predicted).

In results presented at IDWeek2019, investigators demonstrated a distinct “signature” of AFM in blinded cerebrospinal fluid samples >80% of the time.

The risk of incident DM was more substantial with INSTIs vs. NNRTIs (HR=1.22; CI: 0.95-1.57), and a similar rate was noted with PI- vs. NNRTI-initiators (HR=1.25; CI: 1.05-1.49).

Two late breaker abstracts at IDWeek 2019 provide an in-depth analysis of the 2018-19 measles outbreaks in the state of New York.

While hospital-onset SAB accounted for about 1 in 10 cases, it is associated with 182% higher complication rate and 144% higher mortality than community-onset infections.

The most common presentation for pediatric invasive aspergillosis patients was a pulmonary infection.

Carlos del Rio, MD, co-director of Emory Center for AIDS Research, discusses the collaboration across specialties that is inherent in infectious disease.

RBX2660, a microbiota-based drug, was safe and efficacious for preventing recurrent C diff infection with clinical durability to 24-months after treatment, independent of age or sex.

The phase 1/2 trial of a prime-boost vaccine to prevent chronic HCV infection was completed in an at-risk population of in people who inject drugs.

A team of investigators set out to evaluate whether TORC1 inhibitor RTB101 could increase antiviral gene expression and decrease the incidence of RTIs in older adults.

The analysis of the survey responses found a statistically significant association in denial of the biomedical discourse and dissatisfaction or mistrust of the Ebola response as indicators of social resistance.

In the Opening Plenary of IDWeek 2019, 2 bright lights in infectious disease research spoke on the sea-change brought by genomics to biomedicine and the response to infectious disease outbreaks.

A total of 168,420 dental visits included antibiotic prophylaxis, 136,177 (80%) of which were deemed unnecessary.

Adverse events led to premature discontinuation in 14% (21) of ISA patients and 53% (85) of patients receiving VOR prophylaxis.

A presentation at IDWeek 2019 gives hope for the rapid identification and isolation of extensively drug-resistant organisms.

Investigators observed no moderate, severe, cumulative, or dose-limiting adverse events leading to discontinuation, and ACX-362E was generally well-tolerated at all dose levels.

In a new study, a team of investigators set out to determine if oritavancin use can reduce the sequelae from ABSSSI treatment failures, while also preventing infection recurrences and improving patient outcomes.

An oral abstract session on public health covers the full gamut of new outbreaks, challenges from around the world.

Investigators assessed rates of all-cause mortality at Day 14 for Cefiderocol and meropenem in patients with nosocomial gram-negative pneumonia.

When it came to infection prevention measures, 5 of the 9 Orange County facilities with C auris displayed hand hygiene adherence < 50%, 3 had limited access to alcohol-based hand rubs, and < 60% of assessed high-touch surfaces were clean.

As September draws to a close, the Contagion® editorial team is recapping the trends and top infectious disease news of the month.