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Alternative Antiretroviral Medication Delivery Systems Emerge to Treat, Prevent HIV InfectionNovel modes of delivery are imperative to improve HIV suppression and prevent transmission.
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FDA Grants QIDP & Fast Track Designations for SCY-078 to Treat Vulvovaginal CandidiasisThe FDA has granted QIDP and Fast Track Designations for the oral formulation of SCY-078 for the treatment of vulvovaginal candidiasis.
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Strategic Alliance Formed to Advance RNAi Therapeutics for Infectious DiseasesAlnylam Pharmaceuticals announces exclusive licensing agreement with Vir Biotechnology for the development and commercialization of RNA Interference therapeutics for infectious diseases.
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New Rules Expand Application of the NTAP Program for Innovative AntibioticsTo better support the use of critical antibiotics, the Centers for Medicare & Medicaid Services revised the rules governing reimbursement for qualifying antibiotic products. For these changes to succeed, hospital systems will need to make adjustments.
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FDA Guidance Synchronizes Launch of Antimicrobial and AST DeviceThe FDA has finalized its guidance on how to synchronize development of antimicrobials and antimicrobial susceptibility test devices.
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Final Diagnosis: Disseminated Kaposi Sarcoma With Tonsillar and Pulmonary InvolvementA shocking find on a CT scan leads to an unexpected diagnosis.
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Vaccination in 2019: Daunting Challenges and OptimismThe Closing Plenary of IDWeek 2019 discussed the challenges of vaccination and the optimism that we may be on the path to eradicating some global infectious diseases.
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Don't Rush Science: Maintaining Ethics in Exploring Countermeasures for COVID-19Michael K. Gusmano, PhD, discusses the importance of maintaining ethical standards in research evaluating potential therapeutics and vaccines for COVID-19.
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Can Fidaxomicin Provide Effective C difficile-Associated Diarrhea Prophylaxis for HSCT Recipients?Clostridium difficile rates in stem cell transplant patients are approximately 9 times greater than in hospitalized patients, with rates about twice as high in allogeneic vs autologous transplants.
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ACIP Endorses Shingrix As Preferred Shingles Vaccine for Adults Aged 50 & OlderThe CDC’s ACIP recommends newly FDA-approved Shingrix as the preferred vaccine for the prevention of shingles in individuals 50 years of age or older.
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New and Pipeline Antiretroviral Agents for the Treatment of HIV-1 InfectionThis article seeks to review newer ART agents, as well as those in later stages of drug development, for the treatment of HIV-1 infection.
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Get Off the SOFA! Introducing the Quick Pitt Bacteremia ScoreThe quick Pitt Bacteremia Score offers accuracy comparable to the original version's across multiple infections, and maintains ease of use.
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The Great Debate: Polymyxin B Versus Polymyxin EAs we await novel compounds from a relatively apathetic industry, we are resurrecting antibiotics of which we have an outdated understanding. and that carry the potential for substantial side effects: polymyxins.
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Biktarvy: A Regimen of Choice for HIV TherapyThe new single-tablet regimen provides a safe and effective treatment option for patients with HIV.
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Multidrug-Resistant Pseudomonas aeruginosa Infections: Hard to Treat, But Hope on the Horizon?Two recently approved agents offer significant activity against these hard-to-treat conditions.
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COVID-19 Treatment: Updates March 19-24, 2020Erin K. McCreary, PharmD, BCPS, BCIDP; and Jason M. Pogue, PharmD, BCPS, BCIDP, provide an update of published literature on experimental treatments for COVID-19 from the past week.
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Implications of the 21st Century Cures Act on Antibiotic Drug DevelopmentExperts weigh in on what Congress is doing to tackle the threat of antibiotic resistance.
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Appropriate or Not? A Look at Antibiotic Use in the Emergency DepartmentThis In the Literature piece details a study evaluating the appropriateness of prescriptions in comparison to evidence-based guidelines and expert opinion.
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Strep Throat—To Fear or Not to Fear (Again)?Reports of serious consequences from severe streptococcal infections have caused fear among the general public, but is this fear warranted?
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Ending the HIV Epidemic Initiative: A Snapshot From the Trenches, 1 Year LaterFunded jurisdictions scramble to meet daunting deadlines yet maintain optimism that the new federal initiative can end flat funding and catalyze progress.
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COVID-19: Finally an ELISA EmergesOver time we will learn the best utility of the ELISA test, as SARS-CoV-2 is here to stay.
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Diagnostic Stewardship: Beyond Managing Bloodstream InfectionsDiagnostic stewardship is a novel concept related to modifying the process of ordering, testing, and reporting with the goal of decreasing unnecessary testing and treatment, working upstream and synergistically with antimicrobial stewardship principles.
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Student Pharmacists Valuable Resources for Vaccination CampaignsIn addition to licensed pharmacists, student pharmacists can play an important role in helping more Americans get vaccinated by participating in immunization campaigns throughout their communities.
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Maximize Contact and Minimize IsolationOptimizing the relationship between infection prevention and antimicrobial stewardship.
