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FDA Approves Oral Sulopenem (Orlynvah) for Uncomplicated Urinary Tract InfectionsIterum Therapeutics receives approval for Orlynvah as the first oral penem for treating uncomplicated urinary tract infections in adult women with limited treatment options.
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The Multi-Drug Resistant Organism NetworkA collaborative, international effort aims to answer tough antimicrobial resistance questions.
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Preventing Multidrug-Resistant Spread in Healthcare FacilitiesThe interconnectedness of many healthcare facilities such as nursing homes, hospitals, and long-term acute-care hospitals means a significant chance of multidrug-resistant organism transmission when patients shuttle between facilities.
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Shoutout to the Stewards: Holiday EditionContagion® radio is here to bring joy with every new antibiotic alert!
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How Obamacare Will Affect HIV/AIDS PreventionNoting successful HIV/AIDS prevention efforts rely on early diagnosis, an analysis estimates that improved access to health insurance through the Affordable Care Act will increase the number of patients getting tested for HIV by nearly 500,000 over a 5-year period, though that impact would be amplified if all US states opted to expand Medicaid coverage.
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President Trump and First Lady Test Positive for COVID-19President Donald Trump broke the news last night via Twitter.
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Taking A Closer Look at Shingrix: The New Shingles VaccineThe only way individuals can reduce their risk of getting shingles is to get vaccinated; luckily, a new vaccine has recently been approved by the FDA.
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An Unknown Contagious Rash: Case Report and Literature Review of Norwegian Crusted ScabiesA patient with HIV and skin lesions should trigger a broad differential.
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Fecal Transplant Benefits C diff Patients Coinfected With COVID-19Treating Clostridioides difficile infection is complicated in patients coinfected with COVID-19. However, a new study suggests a significant benefit of fecal microbiota transplant (FMT) in these coinfected patients.
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Four Fungal Horsemen: Emerging Trends in Fungal Disease EpidemiologyNew public health perspectives on aspergillosis, sporotrichosis, histoplasmosis, and coccidioidomycosis.
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Antiretroviral Safety in Pregnancy: Focus on Dolutegravir, Integrase Inhibitors, and Neural Tube DefectsThere has been increasing interest in the association between neural tube defects, dolutegravir, and integrase inhibitors as a class since 4 cases were reported in 2018.
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Pediatric Hexavalent Combination Vaccine Approved by FDAThe vaccine is approved as a 3-dose series, which consists of a 0.5 mL intramuscular injection, administered at 2, 4, and 6 months of age.
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Alternative Antiretroviral Medication Delivery Systems Emerge to Treat, Prevent HIV InfectionNovel modes of delivery are imperative to improve HIV suppression and prevent transmission.
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FDA Grants QIDP & Fast Track Designations for SCY-078 to Treat Vulvovaginal CandidiasisThe FDA has granted QIDP and Fast Track Designations for the oral formulation of SCY-078 for the treatment of vulvovaginal candidiasis.
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Strategic Alliance Formed to Advance RNAi Therapeutics for Infectious DiseasesAlnylam Pharmaceuticals announces exclusive licensing agreement with Vir Biotechnology for the development and commercialization of RNA Interference therapeutics for infectious diseases.
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New Rules Expand Application of the NTAP Program for Innovative AntibioticsTo better support the use of critical antibiotics, the Centers for Medicare & Medicaid Services revised the rules governing reimbursement for qualifying antibiotic products. For these changes to succeed, hospital systems will need to make adjustments.
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FDA Guidance Synchronizes Launch of Antimicrobial and AST DeviceThe FDA has finalized its guidance on how to synchronize development of antimicrobials and antimicrobial susceptibility test devices.
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Final Diagnosis: Disseminated Kaposi Sarcoma With Tonsillar and Pulmonary InvolvementA shocking find on a CT scan leads to an unexpected diagnosis.
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Vaccination in 2019: Daunting Challenges and OptimismThe Closing Plenary of IDWeek 2019 discussed the challenges of vaccination and the optimism that we may be on the path to eradicating some global infectious diseases.
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Don't Rush Science: Maintaining Ethics in Exploring Countermeasures for COVID-19Michael K. Gusmano, PhD, discusses the importance of maintaining ethical standards in research evaluating potential therapeutics and vaccines for COVID-19.
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Can Fidaxomicin Provide Effective C difficile-Associated Diarrhea Prophylaxis for HSCT Recipients?Clostridium difficile rates in stem cell transplant patients are approximately 9 times greater than in hospitalized patients, with rates about twice as high in allogeneic vs autologous transplants.
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ACIP Endorses Shingrix As Preferred Shingles Vaccine for Adults Aged 50 & OlderThe CDC’s ACIP recommends newly FDA-approved Shingrix as the preferred vaccine for the prevention of shingles in individuals 50 years of age or older.
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New and Pipeline Antiretroviral Agents for the Treatment of HIV-1 InfectionThis article seeks to review newer ART agents, as well as those in later stages of drug development, for the treatment of HIV-1 infection.
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Get Off the SOFA! Introducing the Quick Pitt Bacteremia ScoreThe quick Pitt Bacteremia Score offers accuracy comparable to the original version's across multiple infections, and maintains ease of use.
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The Great Debate: Polymyxin B Versus Polymyxin EAs we await novel compounds from a relatively apathetic industry, we are resurrecting antibiotics of which we have an outdated understanding. and that carry the potential for substantial side effects: polymyxins.
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Biktarvy: A Regimen of Choice for HIV TherapyThe new single-tablet regimen provides a safe and effective treatment option for patients with HIV.
