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Antibiotic Stewardship in Outpatient CareAlthough there are challenges for clinical and infectious disease pharmacists when trying to apply this concept, here are some considerations and strategies to employ stewardship in this setting.
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340B Drug Pricing Program: What Is It and Why Is It Important?The 340B program has had a great impact on access to HIV treatment and prevention services in the US.
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Mixed Fungal Brain AbscessClinicians review a patient case including diagnosis, treatment, and follow-up.
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MRNA COVID-19 Vaccines and Male FertilityAccording to a small study, the Moderna and Pfizer COVID-19 vaccines do not impact male fertility.
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Multidisciplinary Perspectives on HIV TreatmentA multidisciplinary panel concludes a discussion on best practices for managing patients with HIV in various healthcare settings and overcoming social health disparities.
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COVID-19 Booster Shots and the FutureKey opinion leaders provide some advice for the public regarding COVID-19 booster shots and look to the future of the pandemic.
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Long-Acting Antiretroviral Therapies for HIV Treatment and PreventionMore treatment options and modalities are now available for patients.
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Identifying Disparities in Sepsis Diagnosis for Unbiased CareRisk of inaccuracy with pulse oximeters and clinician knowledge gaps in people of color may affect sepsis evaluations and impact treatment plans.
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Future Directions for Managing COVID-19 and InfluenzaGeorge Loukatos, MD, shares clinical pearls for the management of the SARS-CoV-2 and influenza viruses.
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Challenges in the Management of Mycobacterium abscessus ComplexThis pathogen is the third most frequently isolated nontuberculous mycobacteria seen in the United States. Here is a review of how it presents and treatment options.
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Contemporary Issues on the Treatment of Women Living with HIV in the USThe increasing presence of multiple non-AIDS comorbidities in women and others living with HIV challenges clinicians to steer away from the approach of optimizing individual chronic conditions but to think more holistically.
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From Pandemic to EndemicA research agenda focusing on breakthrough infections, reinfections, severity, and sequelae is needed to inform clinical practice when COVID-19 emphasis shifts from eradication to living with the disease.
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So You Made the Decision to Implement Vancomycin AUC Dosing. Now What?Since the vancomycin guideline update, institutional leaders have been faced with the challenge of implementing and monitoring AUC-guided dosing.
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The ART of Implementing an Antiretroviral Stewardship ProgramBy addressing ART-related medication errors and increasing linkage to care, antiretroviral stewardship programs can improve management of inpatients with HIV.
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Federal Agencies Work to Make RSV Monoclonal Antibody Immunization Accessible to FamiliesThe FDA and CDC announced the availability of additional doses of nirsevimab-alip for infants at high-risk of infection.
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Molecular Diagnostics for Bacterial Pneumonia Need Testing StewardshipOngoing education and proven outcomes need to aid this form of testing.
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An Update on LenacapavirThis new antiretroviral with a unique mechanism of action may be lifesaving for those with treatment-resistant HIV infection.
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Communication Breakdown: Dissemination of Public Health InformationImprecise language can fuel infodemics and misinformation and damage public trust.
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To Prophylax or not to Prophylax: Preventing CDIClinicians look at optimal approaches for trying to avoid Clostridioides difficile infection (CDI).
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So You Made the Decision to Implement Vancomycin AUC Dosing. Now What?Since the vancomycin guideline update, institutional leaders have been faced with the challenge of implementing and monitoring AUC-guided dosing.
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Outpatient Antimicrobial Stewardship: The Keys to Developing a Successful ProgramThis form of stewardship can reduce unnecessary antibiotic prescribing, reduce costs, and optimize patient outcomes.
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Going Viral on Social Media: Integrating Digital Tools into Pharmacy RotationsIn the latest Bench to Bedside column, 2 clinicians discuss the benefits of utilizing social media for learning.
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Bad Bugs, New Drugs: A Discussion of Selected New Therapeutics From IDWeek 2022Cefepimetaniborbactam may represent a safe and effective carbapenemsparing agent in cUTI and AP, whereas ridinilazole may play an important role in treating CDI.
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Tricky Infusion Issues and Potential Solutions: OPAT EditionOutpatient parenteral antimicrobial therapy (OPAT) offers benefits for patients as well as providing cost effectiveness; however, it is not without its challenges. Two clinicians provide insights on this modality.
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Treating Zaire ebolavirus With Ansuvimab-zyklThe recombinant human IgG1κ monoclonal antibody binds and neutralizes the virus.
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Reduced-Dose Trimethoprim-Sulfamethoxazole Effective in Treating Mild to Moderate Pneumocystis jirovecii PneumoniaHere is a review of using this therapy in this patient population.
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New Recommendations for Antibiotic Prophylaxis Prior to Dental ProceduresThe American Dental Association (ADA) has updated patient profiles on who should be indicated for antibiotic prophylaxis.
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Precision Dosing of To-Marrow: Linezolid Therapeutic Drug MonitoringEmerging literature suggests therapeutic drug monitoring for this antimicrobial to minimize the risk for linezolid-associated toxicities while maintaining efficacy in select populations.
