Antibiotics

Investigators of a recently published manuscript surveyed hospitals participating in the Michigan Hospital Medicine Safety Consortium in order to evaluate contemporary practices and needs related to antibiotic stewardship.

Jason Gallagher, PharmD, FCCP, FIDSA, BCPS, describes the current state of antimicrobial stewardship efforts.

Exploring the antibiotic commercial conundrum. ​

Jason Gallagher, PharmD, FCCP, FIDSA, BCPS, discusses some of the broader themes in ID over the course of 2019.

Jason Gallagher, PharmD, FCCP, FIDSA, BCPS, discusses noteworthy infectious disease papers published in 2019.

Here is a look back at approvals, clearances, and authorizations granted by the US Food and Drug Administration for infectious disease products in 2019.

Investigators assessing how frequently antibiotics are prescribed without a documented indication discovered that 18% of antibiotic prescriptions had no documented indication in a nationally representative sample of ambulatory clinic encounters.

Mouse models suggest that giving patients with cancer a dose of vancomycin before radiation may prepare the immune system to attack tumor cells more effectively.

A new study shows that patients with medical devices were more likely to have resistant infections.

Ertapenem and daptomycin are commonly used in OPAT plans because they are broad-spectrum antimicrobial agents, despite their high cost.

The CDC’s latest report highlights higher rates of infections in the US, but this week let's focus on awareness so we can combat the threat of resistance.

A prediction model using prior health care exposure information could discern patients likely to harbor carbapenem-resistant Enterobacteriaceae at time of hospital admission.

Treating patients who have skin and soft tissue infections with a single dose of oritavancin may lower hospital admission rates compared to vancomycin, at a similar cost.

A rapid increase in antibiotic prescriptions before diagnosis with such conditions as COPD, heart failure and asthma, suggests these conditions may often be misdiagnosed as infections, according to a new study.

Amidst growing concern about antibiotic resistance, a new class of antibiotics may help in the fight against gram-negative bacteria.

A total of 168,420 dental visits included antibiotic prophylaxis, 136,177 (80%) of which were deemed unnecessary.

Pharmacists could help improve antibiotic treatment of pediatric patients, particularly in facilities that don’t regularly treat children, according to a recent review article.

Antibiotic treatment for more than 20 months may cause lasting changes in the gut microbiota of preterm infants, a new study suggests.

Between July and August 2016, a decrease of 10.4 days of therapy per 1000 patient days (7.6%; P = .002) was observed.

As a growing number of infections become resistant to antibiotic medications, it is becoming crucially important that providers not only practice antibiotic stewardship but also use effective antibiotics when they are needed.

A new report on US prescribing trends and stewardship initiatives assesses the scope of the antibiotic resistance problem and lays the groundwork for solutions.

We're failing to make sure cultures are indicated properly in catheterized patients, which can lead to serious disruptions of care.

Matthew Girgis, PharmD, PGY-2, discusses why it's advantageous to decrease patient exposure to vancomycin.

Recent commentaries—1 optimistic, the other less so—shed light on the challenges ahead and how we can hope to overcome them.

One of the biggest studies to-date on the relationship between cefepime plasma concentrations and neurotoxicity has identified which patients are at greatest risk.

Glenn Tillotson, PhD, explains how inappropriate empiric therapy can drive poor outcomes.

Investigators from the Washington State Department of Health set out to identify ways to leverage technology to increase public awareness of the importance of antimicrobial stewardship.

Dentists write 1 in 10 antibiotic prescriptions in the United States and a new study has found that more than 80% of the antibiotics prescribed for infection prophylaxis are unnecessary.

Antibiotics and chest x-rays are routinely used to diagnose and treat pediatric CAP, despite guidelines advising the contrary.

A study led by Cleveland Clinic investigators confirms that placing implantable cardiac devices inside an envelope that emits antibiotics slashes infection rates.