Antibiotics

Efforts such as improved indication documentation and antimicrobial stewardship involvement may improve patient outcomes in some patients who are on outpatient parenteral antimicrobial therapy (OPAT) for ease of administration (EOA) that are readmitted to the hospital.

New software to facilitate prior authorization helped streamline the approval process and increase antimicrobial use tracking at the Hospital of the University of Pennsylvania.

Study results indicate that clinicians start prescribing new drugs off-label almost as soon as the drugs become available.

Researcher give insight into the importance of antibiograms in outpatient management of urinary tract infections

A look into the challenges of including infection preventionists in antimicrobial stewardship programs.

New surveillance report sheds light on meningococcal disease rates among HIV-infected MSM.

Plenty of research has gone into the causes and progression of Alzheimer’s disease. Now a new effort aims to make the case that scientists have been looking in the wrong direction.

Investigators find iclaprim to be active against a worldwide collection of drug-susceptible and drug-resistant beta-hemolytic streptococci from patients with skin and skin structure infections.

By itself, the POET trial should not fundamentally change the current approach to infective endocarditis treatment.

The program calls for new research and development incentives, veterinary stewardship, and enhanced surveillance.

We’ve rounded up a list of important US Food and Drug Administration (FDA) and US Department of Agriculture (USDA) recalls from this past week.

Stay up-to-date on the latest infectious disease news by checking out our top 5 articles of the week.

A new study underscores components to antimicrobial resistance that we may be ignoring.

Findings from a pair of studies from investigators in Israel suggest that probiotic supplements may not be as beneficial as previously thought.

Julie Ann Justo, PharmD, MS, BCPS-AQ ID, explains how rapid diagnostics interplay with prediction scores in antimicrobial stewardship programs.

We’ve rounded up a list of important US Food and Drug Administration (FDA) and US Department of Agriculture (USDA) recalls from this past week.

Do ancient medicinal treatments hold potential for future antimicrobial efforts?

The conventional approach to fighting resistant E coli infections typically involves the use of no more than 2 antibiotics; however, combining as many as 5 may be the trick to fighting these infections.

A new analysis details the potential clinical and economic benefits of implementing antimicrobial stewardship programs in hemodialysis facilities.

An understanding of the limitations in their functionality and strategies for more appropriate applications are necessary for clinicians.

Stay up-to-date on the latest infectious disease news by checking out our top 5 articles of the week.

Aerosolized antibiotics are a reasonable adjunctive option to treat multidrug-resistant gram-negative pneumonia due to excellent pulmonary concentrations and few adverse effects.

Since its implementation in December 2016, use of a ceftolozane-tazobactam order set at Marin General Hospital has advanced antimicrobial stewardship efforts.

Contagion® editor-in-chief, Jason C. Gallagher, PharmD, FCCP, FIDSA, BCPS, affirms that the health care industry needs to hit the reset button on how antibiotics are developed.

In addition to other updates, new breakpoints have been added for cefiderocol and meropenem-vaborbactam.

Gram-positive multidrug-resistant infections may be managed effectively with a single dose of long-acting lipo­glycopeptide antibiotics in the outpatient setting; however, careful patient selection is important for maximizing the cost-benefit of these relatively expensive drugs.

Targeting stewardship interventions to the morning hours may have a greater impact than afternoons and nights.

Ellie J C Goldstein, MD, discusses how physicians need to rely on the data that is available when selecting an antibiotic.

Gram-negative organisms are showing up at higher rates in seriously ill pneumonia patients. What are the best antibiotics to prescribe, given the real risk of death and the need to avoid contributing to drug resistance?

Julie Ann Justo, PharmD, MS, BCPS-AQ ID, discusses the source of prediction scores and how antimicrobial stewards work in concert with other clinicians to develop prediction scores.