Antibiotics

In the latest article from SIDP, here is a look at therapy options addressing this emerging clinical challenge.

Kevin J. Downes, MD, and Contagion® Section Editor Conan MacDougall, PharmD, MAS, BCPS, BCIDP, discuss these important topics as another season approaches.

Findings increasingly suggest the mortality risk may be reduced by initiating daptomycin within 3 days of infection.

Infection preventionists at UCLA used active surveillance screening and technology to take a proactive approach to staving off any potential outbreaks of the emerging fungal infection in their health system.

The interconnectedness of many healthcare facilities such as nursing homes, hospitals, and long-term acute-care hospitals means a significant chance of multidrug-resistant organism transmission when patients shuttle between facilities.

The cases include children and adults across four states.

Considering the care team members who need to help infectious disease specialists and pharmacists carry the stewardship torch.

A conversation with Anna Legreid Dopp, Pharm. D.

The American Dental Association (ADA) has updated patient profiles on who should be indicated for antibiotic prophylaxis.

Patients failed to respond to currently available drugs in initial documented instances of spread.

A seven-day course of antibiotics was as effective as 14 days in treating urinary tract infection in afebrile men.

A research team working across several nursing homes sought to reduce antimicrobial use.

The Pasteur Act in Congress is designed to incentivize pharmaceutical companies to develop new antibiotics.

Exposure to antibiotics in childhood was found to have small effect on trajectory of body mass index milestones.

A recent press briefing by the Infectious Diseases Society of America (IDSA) addressed the need to have new antibiotics in the pipeline to answer the rising challenge of drug resistance.

Providing "social normative feedback" to physicians succeeded in lowering antibiotic treatment duration and cost, with less effect on prescription volume.

Increased respiratory viral testing for COVID-19 and Influenza could have contributed to improved antibiotic prescribing for respiratory symptoms.

Post-intervention saw 55% of patients receive overall guideline-concordant antibiotics.

Average annual discharges were significantly higher in participating hospitals.

The challenging search for a metric that effectively evaluates an ASP’s direct impact on appropriate antimicrobial use and improved patient outcomes.

QPX9003 was developed through an NIAID-supported drug discovery collaboration with world experts.

International travelers acquire antimicrobial resistance genes, including some not included in databases, a recent study confirmed.

Investigators in Brazil attribute Trichosporon asahii fungemia in critically ill COVID-19 patients to “overexposure” to antibiotics and corticosteroids.

Paratek’s omadacycline (Nuzyra) is granted approval for an oral-only dosing regimen in adults.

Rapid respiratory virus test results for children in an emergency department could be received too late to inform antibiotic prescribing.

New research from Emory show a significant difference in institutional antibiotic prescribing after education on the value of PCT testing in infected patients last year.

The study authors looked at previously published papers focused on carbapenems, fluoroquinolones, and third-generation cephalosporins.

A conversation on antimicrobial stewardship with Kushal Naik, PharmD, MBA.