Antibiotics

The urgent care setting is a prime target for antimicrobial stewardship efforts as it becomes an increasingly prevalent form of healthcare delivery.

Sulopenem was superior to ciprofloxacin for the treatment of uncomplicated urinary tract infections.

The composition of the gut microbiome is easily disrupted by antibiotics, leaving the host susceptible to further infection or other disturbance of gut flora that can lead to both short- and long-term deleterious effects.

Antimicrobial-resistant infections, in particular those caused by gram-negative pathogens that also produce extended spectrum β-lactamases (ESBL), represent a growing threat across the globe as investigators race to develop novel therapeutics

Antibiotics are compared to surgery for appendicitis in light of patient concerns about hospitalization and hospital concerns about resources during COVID-19.

Dr. Debra Goff describes the rush to "Just in Case" prescribing of antibiotics early in the COVID-19 pandemic, when less was known about the clinical course of the disease.

The time to first antibiotic dose is an important step of this new program, however it may require an audit after review according to a new study.

About 1 in 5 patients with bloodstream infections received discordant empirical antibiotic therapy, increasing their risk of mortality independent of sepsis or septic shock, a new study found.

New guidance from the Infectious Diseases Society of America offers timely practice advice for the clinical treatment of three of the most common drug-resistant pathogens.

Soon after visiting 38 hospitals in Michigan, over half of patients hospitalized with suspected COVID-19 received antibiotics.

A University of Maryland Professor of Pathology explains that SARS-CoV-2 has unique ways of evading detection.

Robert H. Christenson, PhD, describes the threat of AMR and the role of relevant diagnostics in clinical settings.

The challenges of making formulary and clinical decisions based on regulatory studies are significant and the need for real-world clinical experience is increasingly important.

Dr. Pol Vandenbroucke describes the individual and collective risks associated with rising antibiotic resistance.

Dr. Pol Vandenbroucke talks about what makes antibiotic stewardship so important to clinicians and researchers.

Dr. Pol Vandenbroucke explains how the development of health and civil society infrastructure around the world helps to slow antimicrobial resistance.

Dr. Pol Vandenbroucke describes the alarming global threat of antimicrobial resistance.

Biopharmaceutical companies create nearly $1 billion fund to aid much needed pipeline for antimicrobial resistance.

Hospitalized patients with unverified penicillin allergies may unnecessarily face greater risk of adverse drug events when given broader spectrum alternative antibiotics, according to a new study.

Hollow-fiber infection model (HFIM) facilitates comparison of intermittent vs continuous infusion of ß-lactam antibiotic for K. pneumoniae

Despite guidelines discouraging use of anti-pseudomonal β-lactams and fluoroquinolones for community-acquired complicated intra-abdominal infection, about 75% of lower-risk patients are receiving such treatments, a new study found.

An overview of 3 recent infectious disease news stories.

Providing oral antibiotics to people who inject drugs with infections may reduce hospital readmissions.

Investigators from the Universitat Autònoma de Barcelona have identified links between antibiotic resistant S maltophilia phenotypes and "quorum sensing."

Early administration of such therapies in this patient group not shown to help mortality rates.

A review of 61 clinical trials suggests that acute uncomplicated cystitis in adult women could be treated with shorter duration of antibiotics in some cases.

Cefiderocol functions as a siderophore and has a novel mechanism of action which penetrates the outer cell membrane of Gram-negative pathogens.

Investigators in Italy found ceftolozane/tazobactam to be an effective treatment for some patients with severe ESBL-E infections.