June 25th 2025
Marketed as Orlynvah, oral sulopenem from Iterum Therapeutics was FDA approved last fall for uncomplicated urinary tract infections and has shown efficacy against infections caused by Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis.
Antibiotic Prescriptions Spike Before Diagnosis of Health Condition
November 1st 2019A rapid increase in antibiotic prescriptions before diagnosis with such conditions as COPD, heart failure and asthma, suggests these conditions may often be misdiagnosed as infections, according to a new study.
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Clinicians Only Using New Antibiotics in Quarter of CRE Infection Cases, New Study Finds
August 29th 2019As a growing number of infections become resistant to antibiotic medications, it is becoming crucially important that providers not only practice antibiotic stewardship but also use effective antibiotics when they are needed.
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Prophylactic Antibiotic Reduces Risk of Infection by 56% Following Operative Vaginal Birth
May 29th 2019Although antibiotic prophylaxis for new mothers is common following caesarean section births, a new study provides evidence of benefits on infection reduction in women following operative vaginal birth.
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2019 Fluoroquinolone Breakpoints Revised for Enterobacteriaceae and Pseudomonas aeruginosa
May 17th 2019A revision to the fluoroquinolone antimicrobial susceptibility testing breakpoints for 2 bacteria comes following evidence that previous breakpoints were too high to detect low-level antibiotic resistance.
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CAMERA2: Combination Therapy for MRSA Bacteremia Effective but Linked to Higher Mortality, AKI Rates
April 16th 2019Investigators found increased mortality in the combination arm where 21% of patients died vs 16% in the standard therapy arm, although the number of patients with persistent bacteremia at day 5 in the combination arm was significantly reduced compared with standard therapy.
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