Antibiotics

The National Academies report reviews several challenges, and ways to overcome them for optimal antimicrobial stewardship.

CEO Christopher Burns spoke about their investigational therapy pipeline, the long view perspective for the company, and how the federal government’s use of the nomenclature innovation might actually hinder incremental improvements in antibiotic development.

Betsy Wonderly-Trainor discusses CARB-X's mission to fund novel antibiotics, preventatives, and diagnostics in the fight against antimicrobial resistance.

India is the world’s leading consumer of antibiotics, and Amita Gupta, MD, is researching how the country can best mitigate the spread of antimicrobial resistance.

Antimicrobial stewardship efforts need infectious disease doctors, but they are in short supply. Telehealth may be the answer.

In the latest article from SIDP, here is a look at the use of various intravenous (IV) antimicrobial therapies to address infections in these patients.

Survey findings show short-term benefits may not translate to long-term optimal outcomes.

A new study in Israel supports the use of a shorter course of antibiotics for the treatment of complicated urinary tract infection in recipients of kidney transplants.

This novel, rapid diagnostic assay uses polymerase chain reaction and magnetic resonance to identify the 5 most common Candida species.

Here is a review the mechanisms that lead to resistance, including risk factors.

Providers offer their insights on this important topic.

It can help inform appropriate antibiotic prescribing, but likely would only form part of testing protocol, experts say.

A new study shows Medicare-aged patients being treated in hospitals saw more of these types of infections, creating a greater burden on care and costs, and showing an increased mortality rate.

Massachusetts General Hospital investigated how international travel contributes to the contraction and carriage of antimicrobial resistance (AMR).

This type of stewardship is a means of reducing unnecessary testing, getting the appropriate diagnosis more efficiently, and getting patients the appropriate therapy in a timely manner.

In research presented virtually at IDWeek 2021, investigators with the Centers for Disease Control and Prevention (CDC) conducted a review of nursing home antibiotic stewardship citation deficiencies in order to improve implementation.

The protective effect remained strong through the 18- and 24-month follow-up periods, the study authors said.

A recent study examining trends in time-to-antibiotics among veterans hospitalized with sepsis found that patients received antibiotics faster over time.

The model found patients whose physicians received artificial intelligence-based alerts also spend fewer days in the hospital.

Incidence of cholangitis with mult-drug resistant bacteria was higher among patients who regularly use proton pump inhibitors, a new study in Japan found.

In the latest article from SIDP, here is a look at therapy options addressing this emerging clinical challenge.

Kevin J. Downes, MD, and Contagion® Section Editor Conan MacDougall, PharmD, MAS, BCPS, BCIDP, discuss these important topics as another season approaches.

Findings increasingly suggest the mortality risk may be reduced by initiating daptomycin within 3 days of infection.

Infection preventionists at UCLA used active surveillance screening and technology to take a proactive approach to staving off any potential outbreaks of the emerging fungal infection in their health system.