Prevention

In patients with MRSA bacteremia, implementing AUC/MIC-guided vancomycin dosing resulted in decreased average troughs and a decrease in daily vancomycin dose administered.

The FDA has issued label updates for a handful of fluoroquinolone antibiotics to note the risk of aortic dissections and aortic aneurysms in certain patients.

Understanding barriers and facilitators of PrEP could help improve adherence among young men and transgender women of color, a recent study found.

Vanessa Stevens, PhD, discusses her research on fluoroquinolone and cephalosporin prescribing and rates of Clostridium difficile infections at VA health care facilities.

Surgical-site infection was not found to be associated with duration of prophylaxis, but adjusted odds of AKI and C diff infection increased with each additional day of antimicrobial exposure.

An intervention involving improved communication and antibiotic timeouts in nursing homes reduced the days of antibiotic therapy, according to a recent study.

The rate of health care-associated influenza cases per season decreased from a median of 16.8 cases pre-policy rollout to 5.2 cases post-policy rollout at a large pediatric hospital.

Tristan Ferry, MD, PhD, discusses why there is a need to develop alternatives to treat chronic bone and joint infections.

A shortage of infectious disease physicians should have us all concerned and here's why.

Investigators found increased mortality in the combination arm where 21% of patients died vs 16% in the standard therapy arm, although the number of patients with persistent bacteremia at day 5 in the combination arm was significantly reduced compared with standard therapy.

Rezafungin achieved greater and more prolonged penetration at sites of intra-abdominal candidiasis than micafungin, which correlates with significantly greater activity against FKS-mutant Candida glabrata clinical strains.

Investigators detail the activity of cefiderocol, a novel parenteral siderophore cephalosporin, against carbapenem-resistant clinical isolates.

In a study of hospitalized patients across Europe, oritavancin (MIC50/MIC90, 0.03/0.06 mg/L) inhibited all S aureus isolates at ≤0.12 mg/L (susceptible breakpoint).

Ignacio Martin-Loeches, MD, PhD, discusses the efficacy outcomes of the ASPECT-NP trial evaluating ceftolozane/tazobactam for the treatment of nosocomial pneumonia.

A large percentage (96%) of health care worker respondents reported feeling confident in their knowledge of antibiotic resistance, but only 60% answered the 7 key questions correctly.

A new study showed no statistically significant reduction in clinical cultures between chlorhexidine bathing and routine care.

With the proper use of antiretroviral therapy and pre-exposure prophylaxis, the risk of HIV transmission has never been lower. So why do some practitioners hesitate to endorse condomless sex?

Investigators sampled 6 ball pits in physical therapy clinics throughout Georgia to determine the level of microbial colonization.

Warnings and concerns regarding fluoroquinolones are on the rise, but the antibiotics still play a role, albeit more limited, in the treatment of various infectious diseases.

Contagion® caught up with William Schaffner, MD, medical director of the National Foundation for Infectious Diseases, to discuss the highlights from this week’s NFID Annual Conference on Vaccinology Research.

Contagion® is reflecting on the advancements in treatment and prevention that have been made in infectious diseases while identifying areas that need further improvement to reduce preventable deaths globally.

A commentary on β-lactam combination therapy for methicillin-resistant Staphylococcus aureus bacteremia.

An intradermal Ebola vaccine candidate shows promise as a safe, temperature-stable, and effective option for preventing outbreaks, new data show.

The latest case cluster in the United States has led a university to change policy regarding the MMR vaccine.

A new study found an average decrease of sexual anxiety by 0.27 points when participants were on PrEP compared with before treatment.

To shed light on the current measles outbreaks, Contagion® is launching a video series featuring the perspectives of 2 medical experts.