COVID-19 Prophylactic Evusheld Not Expected to Neutralize New Omicron XBB.1.5 Variant
Evusheld, the only FDA-approved COVID-19 pre-exposure prophylactic, is anticipated to be ineffective against the emerging XBB.1.5 variant.
VV116 Vs Paxlovid Shown to Be Noninferior in Adults at Risk of Severe COVID-19
The investigational antiviral showed the potential of another therapy that could benefit this patient population that is at risk for hospitalization and death.
Diagnostic Stewardship is a Novel Concept That Will Influence Treatment Protocols
Newer diagnostic technologies can play a role in identifying specific bacterium, decrease the time to optimal therapy, and offer the possibility of better outcomes.
Certain Genes May Naturally Protect Against Severe COVID-19
A Brazilian study of people 90 years and older who easily recovered from COVID-19 identified specific genetic components that may have provided protection.
FDA Grants Emergency Use Authorization for Monkeypox Viral Diagnostic
The VIASURE PCR diagnostic is now available under Emergency Use Authorization in laboratories for persons with a suspected mpox infection.
A Measles Outbreak Mostly Among the Unvaccinated
Central Ohio has seen 82 pediatric cases since November, and more than a third of children infected have been hospitalized.
This Week’s Top 5 Infectious Disease Stories
So far, these are Contagion's 5 most-read stories of 2023.
FDA Accepts BLA for Nirsevimab for RSV Prevention for Infants
Developed by Sanofi and AstraZeneca, the single-dose long-acting antibody was designed to help protect all infants from birth through their first respiratory syncytial virus (RSV) season.
Vaxcyte’s Pneumococcal Vaccine Receives FDA Breakthrough Therapy Designation
The 24-valent investigational pneumococcal conjugate vaccine, VAX-24, met its primary endpoints in a phase 1/2 trial.
In the Aftermath of the Pandemic, IDSA Looks to Address COVID-19's Health Care Disparities
A new Infectious Diseases Society of America (IDSA) board member and vice president offers some insights on the leadership’s goals and direction for 2023.
FDA Accepts BLA for Pfizer Meningococcal Vaccine
The company’s vaccine candidate, MenABCWY, which is indicated for adolescents was given a Prescription Drug User Fee Act (PDUFA) goal date for later this year.
What We Know About XBB.1.5, the New and Highly Contagious Omicron Subvariant
In just a month, the XBB.1.5 variant went from causing 1% to over 40% of new COVID-19 infections.
Cyproheptadine Arm of COVID-19 Treatment Study Terminated
Due to negative results, the I-SPY COVID Trial is no longer evaluating cyproheptadine to treat critically ill COVID-19 patients.
Shifting to Shorter Courses of Antibiotic Therapy for Common Pediatric Infections
In the latest SIDP column, two clinicians provide information on recent studies and guidelines directed at antibiotic durations in this patient population.
Molnupiravir Doesn’t Decrease COVID-19 Deaths or Hospitalizations, but May Speed Recovery
Despite failing to meet primary trial endpoints, molnupiravir reduced the length of COVID-19 infection by 4.2 days in vaccinated patients.
Working Toward Eliminating Hepatitis
Health programs and efforts to inform the public about the importance of sharing liver education can play a major role in prevention as well as patient care.
How the COVID-19 Pandemic Changed State-Level Cigarette Sales
During the COVID-19 pandemic, cigarette sales differed from projected sales volume. One study examined these trends at the state level.
STIs: Neglected During COVID-19
Sexually transmitted infections (STIs) received little attention during the pandemic, but the truth is the STIs did not stop infection increases shortly after the quarantine.
Medical Masks Or N95s For COVID-19 Protection in Health Care?
Although medical masks were noninferior to N95 in a multinational study of frontline health care workers, variability in circumstances between countries prevented researchers from drawing firm conclusions.
A Rare Case of Positive Heterophile Antibody in a Patient With West Nile Virus
This unusual Case Study describes a young woman who
presented with an acute onset of headaches and dizziness and was found to have aseptic meningitis.
The Top 5 Video Interviews of 2022
A look back on some of the significant discussions with clinicians, researchers, and infectious disease stakeholders.
Employee Health After the COVID-19 Pandemic: Stronger Than Yesterday
For providers on the front lines, lessons learned can help inform
strategies to enhance the protection of their health going forward.
Updates and Controversies in Necrotizing Soft Tissue Infections
Changes in microbiology and antimicrobial resistance patterns warrant reevaluation of our current therapies for this condition.
Preparing for the Next Long-acting Antiretrovirals
Clinicians can make room for infrequent treatment options as patients enjoy their daily lives.
The Year's Top COVID-19 Stories
New booster shots, antigen testing, and a shrinking incubation period: these were the top COVID-19 stories of 2022.
Why Aren’t We Better Protecting Our Youngest Children Against Infections?
Vaccinations and mitigations for COVID-19 and other respiratory viruses have not been made a priority for young children. Let’s change this before the next big surge hits.
Bad Bugs, New Drugs: A Discussion of Selected New Therapeutics From IDWeek 2022
Cefepimetaniborbactam may represent a safe and effective
carbapenemsparing agent in cUTI and AP, whereas ridinilazole may play an important role in treating CDI.
In Case You Missed It: The Week's Top Infectious Disease Stories
A new monoclonal antibody, invasive group A strep, and genital herpes topped the list of this week's most-read stories.
SHEA: Do Not Screen Symptom-Free Patients for COVID-19 Upon Hospital Admission
The new recommendation from the organization believes it will help avoid delays in patient care.
Would You Try Ceftriaxone for Methicillin-Susceptible Staphylococcus aureus Bacteremia?
This study was one of the largest to address the use of IV ceftriaxone in the context of MSSA bacteremia compared with cefazolin.
2 Clarke Drive Cranbury, NJ 08512