C difficile, Antimicrobials, and the Patients Most Affected
Dr. Teena Chopra discusses the global need to do more to prevent healthcare-associated infections like C difficile in vulnerable patient populations.
European Commission Approves Sanofi-GSK COVID-19 Booster VidPrevtyn
Sanofi and GlaxoSmithKline are the latest companies to bring their COVID-19 booster vaccine to the marketplace with the European Commission’s approval of VidPrevtyn Beta.
New Therapeutic Offers Promise for Recurrent C Diff Infection
An easy-to-administer oral biologic kept repeat C difficile infections at bay in a new study.
Pfizer-BioNTech Adapted Bivalent Booster Neutralizes Emerging Omicron Subvariants
New clinical findings suggest the Pfizer-BioNTech bivalent booster elicited more neutralizing antibody titers for all tested emerging Omicron sublineages, compared to their original COVID-19 vaccine.
RSV Resurges as COVID Pandemic Precautions Recede
Earlier and higher rates of RSV and other respiratory illnesses following reduced COVID precautions challenge capacity of pediatric units.
Infectious Disease Update: This Week's Top Stories
Read and watch the infectious disease trial data shared this week.
Measuring Disease Severity, Quality of Life in Japanese Hepatitis Patients
As viral hepatitis is the most common blood-transmitted infection globally, assessing the toll of hepatitis and hepatitis-related conditions is critical.
Promising Phase 3 Data Suggest Efficacy of Ibrexafungerp for Vaginal Yeast Infection
Dr. Tosin Goje explains the promise of ibrexafungerp for clearing yeast infection and improving quality of life for these patients.
GSK Halts Trials of new UTI Treatment Gepotidacin for Efficacy
The company says it plans to begin talking with regulators next year after seeing positive efficacy data in the trials.
Antibiotic Development: Glass Half Full or Half Empty?
A clinician offers his perspective on what he sees as a clinician and trial investigator in terms of what is in the pipeline and both the encouraging data and uncertainty in therapy development overall.
Opinions of Oral Versus Injectable HIV PrEP in a Racially Diverse Cohort
Concerns of injectable HIV PrEP safety and efficacy demonstrate a need for health care providers to share reliable information with at-risk populations.
Breakthrough Therapy Bulevirtide was Safe, Effective, and Improved Quality of Life for Hepatitis Patients
Three posters on the subject were presented at The Liver Meeting and were among the meeting’s key presentation highlights called “Best of the Liver Meeting.”
Has HIV PrEP Uptake Increased Among High-Risk Persons?
Although HIV PrEP uptake is gradually increasing, usage remains low among key at-risk populations.
Binge Drinking Increases the Risk of COVID-19 Infection
Young women who binge drink, and especially those who use multiple substances, had a higher risk of COVID-19 infection and mental health complications.
Can Stewardship be Applied in ICU Settings?
One clinician discusses strategies in how his institution minimizes the wide spectrum approach to antibiotics as well as tries to prevent potential complications.
Indicators of Severe Outcomes in Chronic Hepatitis B Patients
What are the characteristics and demographics of the chronic hepatitis B patients who develop severe outcomes?
Identifying HABP/VABP Priorities
An ICU hospitalist talks about his criteria and the treatment protocols for these cases.
Moderna Omicron-Targeting Booster Candidates Demonstrate Superiority Over its Spikevax Booster
Safety profile in this study showed the frequency of adverse reactions with these boosters were similar or lower than that of either a second or third dose of the original vaccine.
WHO Identifies Actions to Address Invasive Fungal Infections
The World Health Organization (WHO) describes measures necessary to confront invasive fungal infections from the pathogens posing highest threat and greatest disease burden.
This Week in Infectious Disease: The Top 5 Articles
Looking for the latest developments in infectious disease? Here are the top stories Contagion covered this week.
Protecting Infants, Young Children by Vaccinating Teens and Adults
Dynavax reported results from its phase 1 study looking at its (Tdap-1018 CpG Adjuvanted) Tetanus/Diphtheria/Pertussis booster vaccine.
The Changing Gram-Negative Landscape
In episode 1 of this short video series, a clinician discusses his experience in what his institution is seeing as well as how they handle their treatment protocol and stewardship where possible.
Listeria Outbreak Associated With Deli Meat and Cheese
16 people have been reported to be infected across 6 states resulting in one death and a pregnancy loss in an expecting mother who became infected.
How Did Lifting School Mask Mandates Affect COVID-19 Infections?
In Boston school districts, lifting mask mandates was correlated with an additional 44.9 COVID-19 infections per 1000 students and staffers.
CDI Biotherapeutic RBX2660 Outperforms Placebo in Phase 3 Trial
The closely watched therapeutic candidate led to long-term responses in 90% of patients who benefited from the therapy.
Do People Who Inject Drugs Use HIV PrEP?
HIV PrEP prescriptions increased from 0 among people who use injection drugs, but overall PrEP uptake remains low.
Despite 60% Drop in Hepatitis B Treatment Efficacy, GSK Plans to Continue Trials
Initially, 28-29% of patients with chronic hepatitis B achieved undetectable virus levels after 24 weeks of treatment with GSK’s bepirovirsen, but this dropped to 9-10% of patients during a phase 2b trial.
WHO Ranks Risks of Invasive Fungal Infections
The World Health Organization's fungal priority pathogens list is intended to prompt research, development and policy against the increasing health threat.
Automatic Letters Help Boost Screenings for Hepatitis C
About a third of veterans who received a letter to get tested for hepatitis C did so, according to a study by the Veterans Affairs Greater Los Angeles Healthcare System.
Did the COVID-19 Pandemic Affect Young Women’s Substance Use? Part 1
Studies suggest young women’s substance use is catching up to men's. Tammy Chung, PhD, examined whether this was exacerbated by the COVID-19 pandemic.
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