Respiratory Infections

The Bacille Calmette-Geurin vaccine is typically administered intradermally, which may not generate enough T cells to elicit strong immune responses in the lungs to effectively protect against TB.

In a phase 3 study comparing delafloxacin and moxifloxacin for community acquired bacterial pneumonia, delafloxacin was deemed well tolerated and effective by investigators.

Overall deaths of young children attributable to lower respiratory infections have dropped by more than half in the past 3 decades. However, the rate of death remains far too high considering that most of these deaths are preventable.

This In the Literature piece features a case vignette on the de-escalation of antibiotics for culture-negative pneumonia.

While most influenza vaccines target the binding protein hemagglutinin, a new study shows cross-strain results for treatment and prevention focused on the glycoprotein neuraminidase.

A study by Shikha Garg, MD, MPH, and her team with the US Centers for Disease Control and Prevention boosts the evidence base for the benefit of influenza vaccination.

According to the WHO’s latest Global TB Report, more than 7 million individuals received treatment for the disease in 2018, but funding gaps could stall progress toward ending TB by 2030.

Angela Campbell, MD, MPH, details a study on influenza vaccine effectiveness in children with respiratory illness.

NEJM study suggests testing everyone, regardless of symptoms, can reduce prevalence.