Jonna Lorenz

Investigators in Tennessee detailed associations between seasonal increases in sporadic pediatric cases of norovirus gastroenteritis and reported norovirus outbreaks among older populations.

Modulating gut microbiota could have therapeutic benefits for people living with HIV, according to a recent study that found HIV infection in women was associated with altered gut microbiota and distinct plasma metabolite profile.

Universal newborn screening for congenital cytomegalovirus infection in China could reduce childhood hearing loss cases by 2316 each year, a new study found.

Public understanding of adverse events could be an obstacle in the rollout of vaccines to fight the coronavirus disease 2019 (COVID-19).

Clostridium difficile infection (CDI) was associated with poorer outcomes, including a higher risk of mortality, among patients with chronic pancreatitis, an evaluation of the Nationwide Inpatient Sample database found.

An early trial of fluvoxamine to treat mild coronavirus disease 2019 (COVID-19) showed promising results, suggesting the antidepressant may help ward off clinical deterioration in patients with mild symptoms.

Children who were exposed to antibiotics before age 2 had a greater risk of childhood health conditions like asthma, celiac disease, obesity and ADHD, a new study in Mayo Clinic Proceedings found.

A survey of clinicians found that despite planning for resource limitations during the coronavirus 2019 (COVID-19) pandemic, clinicians still faced difficult decisions at bedside.

Further evidence demonstrating the lack of efficacy of hydroxychloroquine as a treatment for coronavirus disease 2019 (COVID-19) was detailed in a new randomized, multicenter, blinded, placebo-controlled study published in JAMA.

The anti-inflammatory drug infliximab may have a role in treating COVID-19, according to a new study examining how a key enzyme influences viral entry and gut inflammation.

Neurological symptoms of COVID-19 ranging from dizziness to microclots could be the result of destabilization of the blood-brain barrier caused by virus spike proteins circulating in the blood.

A third of patients hospitalized with community-onset Clostridioides difficile infections had recently been discharged from the same hospital, and most of those received antibiotics, according to research presented at IDWeek.

Autoantibodies that attack type 1 interferons, neutralizing the immune system’s ability to block the SARS-CoV-2 virus, were present in 10% of patients with life-threatening coronavirus diseases 2019 (COVID-19) pneumonia, a new study found.

Cefiderocol was noninferior to high-dose, extended-infusion meropenem in terms of all-case mortality in patients with gram-negative nosocomial pneumonia and showed similar clinical and microbiological efficacy to best available therapies in carbapenem-resistant, gram-negative bacterial infections, according to 2 recently released studies.

A new study found most early cases of SARS-CoV-2 infection in Southern California were seeded from Europe rather than Asia, thus shedding light on how the pathogen spread in the United States.

Underlying chronic obstructive pulmonary disease in patients infected with COVID-19 present a variety of challenges for health care professionals, including increased risk for poor clinical outcomes and increased risk of spreading the disease.

Prone positioning has been found to improve outcomes for mechanically ventilated patients with COVID-19, and a new study suggests the strategy may also benefit conscious patients requiring continuous positive airway pressure.

A panel of pediatric infectious diseases experts recommends supportive care only for children with mild or moderate COVID-19 and suggests remdesivir therapy for those with severe illness requiring supplemental oxygen.

HIV stigma had different effects on the rate of HIV testing among men and women in rural Uganda, a new study found.

A small study in Italy suggests that children are less likely than adults to be asymptomatic spreaders of COVID-19.

About 1 in 5 patients with bloodstream infections received discordant empirical antibiotic therapy, increasing their risk of mortality independent of sepsis or septic shock, a new study found.

A new Danish study found no evidence of a causal association between the quadrivalent human papillomavirus vaccination and syndromes with autonomic dysfunction.

Results of the trial of Novavax’s NVX-CoV2373 vaccine have been published in the New England Journal of Medicine, showing the vaccine appeared safe and elicited strong immune responses.

SARS-CoV-2 is unlikely to pass through the breast milk of infected mothers to their infants, according to a recent evaluation of breast milk samples from 18 women who tested positive for the COVID-19.

An observational study in the United Kingdom supports the concepts of a hyperinflammation phenotype for severe COVID-19 cases and could help guide risk assessment, precision medicine, and trial design.

Odds of better clinical status were higher for patients with moderate COVID-19 who received a 5-day course of remdesivir than for those receiving standard care, according to the most recent randomized clinical trial of the antiviral drug.

A pharmacokinetic and safety substudy found that the 50 mg film-coated adult dose of dolutegravir given once daily is safe and effective for children with HIV weighing 20 kg or more.

A new report suggests a personalized approach to sepsis treatment, recommending prompt antimicrobial therapy for the sickest patients and a more personalize approach for those with less severe cases.

Hospitals considering interventions to reduce Clostridioides difficile infections may find that less is more, according to a new study that found daily cleaning with sporicidal products to be the most cost-effective single infection control strategy.