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Proton pumps inhibitors present risks for individuals living with HIV, dalbavancin can treat MRSA-related pneumonia, probiotics prove deadly against C. difficile, patient involvement increases healthcare practitioners’ hand hygiene, and why delafloxacin is a unique antibiotic for skin infections are the topics that make up this week’s Top 5 articles.

Belinda Ostrowsky, MD, MPH, Health Systems Director of Epidemiology, Antimicrobial Stewardship & Infection Prevention, Montefiore Medical Center, and Associate Professor of Clinical Medicine, Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, discusses five stewardship strategies to help reduce healthcare-associated Clostridium difficile rates.

Belinda Ostrowsky, MD, MPH, Health Systems Director of Epidemiology, Antimicrobial Stewardship & Infection Prevention, Montefiore Medical Center, and Associate Professor of Clinical Medicine, Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, discusses limitations to C. difficile testing that could impact stewardship practices in healthcare facilities.