Respiratory Infections

The impact of including patients with advanced disease and the role of comprehensive care in the PALM 007 clinical trial, which evaluated the antiviral tecovirimat for treating monkeypox in the Democratic Republic of the Congo.

The Public Health Agency of Sweden reported the individual sought care at Region Stockholm and has been diagnosed with mpox caused by clade I.

4-way trial assesses non-prescription interventions, including 2 nasal sprays, for reducing seasonal respiratory illness and related antibiotic use.

The federal agency says the ongoing outbreak of the clade 1 variant in the Democratic Republic of Congo has been reported in neighboring countries.

The individuals who worked in an egg layer facility in Colorado were confirmed to have H5N1 and they have reported mild symptoms without hospitalizations.

The company acquired rights from CureVac to develop vaccines for influenza and COVID-19 using the mRNA platform.

The Centers for Disease Control and Prevention (CDC) and the National Foundation for Infectious Diseases (NFID) both weigh in on the evolving summer COVID-19 season, and strategies for prevention.

A clinical stage company, NanoViricides, is moving forward with their investigational drug, NV-387, into phase 2 clinical trials to examine treatment for RSV, influenza, COVID-19.

The $176 million award is for late-stage development of widespread immunization capability against H5 (avian) influenza, should such vaccines be needed.

The case occurred to a man in Colorado who had direct contact with cattle and state public health officials offer details on the patient as well as the risk to the public.

A retracted paper that erroneously claimed the measles, mumps and rubella (MMR) vaccine caused autism has repercussions still being felt today around topics such as vaccination, misinformation and disinformation, and measles incidence rates.

New research offers clues to susceptibility for the antiviral as the CDC updates the public on 2 strains circulating globally.

This man was the first person globally to have been diagnosed with influenza A(H5N2).

This is the second case in Michigan and it is confirmed in another farmworker who worked with infected cattle.

The flight originated from Germany then landed in Los Angeles and made a final stop in Fresno, California with the infected individual. CDC is aiding in tracking down people on these flights to find out exposure risks.

This genomic diagnostic tool aims to support diagnosis, particularly in immunocompromised patients by identifying pathogens associated with pneumonia and other lung infections.

A Michigan farmworker who had regular contact with livestock was confirmed to have contracted the virus.

Both the World Health Organization and FDA have now recommended this particular set of viruses be left off influenza vaccines for the 2024-2025 respiratory virus season. A new study points to further evidence of their extinction.

In a new real-world study, Sanofi and AstraZeneca’s nirsevimab-alip (Beyfortus) demonstrated high efficacy against respiratory syncytial virus (RSV) lower respiratory tract disease (LRTD).

Insights from Pranay Sinna MD on a multicenter prospective cohort study on household contacts.

Both the United Nations and World Health Organization (WHO) discussed the threat of H5N1, and its potential transmission to other mammals and humans.

The streptococcal pneumoniae urine antigen (SPUA) test was studied over the course of a year to determine if it provided any benefits in terms of diagnostic capability or aided in reducing empirical antibiotic use.

In these patient encounters, a deep cough as a symptom raised concerns around pneumonia and may have prompted prescription of antimicrobials, but did not show a resolution of symptoms sooner.

The origins of the recent H5N1 (avian flu) case in Texas remain unknown, but a researcher offers insights into transmission between animals and humans, the likelihood of more cases, vaccine availability, and treatment.

Community acquired pneumonia is often inappropriately diagnosed in hospital admissions, particularly among older adults with dementia, and can lead to in-hospital antibiotic-associated adverse events, such as Clostridioides difficile.

The case was confirmed in Texas and the person was in contact with cows. CDC says the risk for infection remains low.

A new strategy for universal infant immunization in the 2023-2024 RSV season faces implementation and medication access barriers.

Patients hospitalized for suspected community-acquired pneumonia received targeted treatment more quickly with PCR testing than with culture-based diagnostics.

Phase 2 study for the investigational antiviral, ZSP1273 (onradivir), demonstrated safety and efficacy in reducing the time to resolution of symptoms in a multicenter trial.

Group A streptococcal infections outbreak nearly doubles fatalities from the previous year.