RSV Vaccine Effective at Preventing Lower Respiratory Tract Infection in Older Adults
The investigational vaccine was effective in reducing both lower respiratory tract and all respiratory tract infections.
SNG001 Fails Primary Endpoints, But May Alleviate Long COVID Symptoms
Despite no significant reduction in time to discharge or recovery, inhalable SNG001 may lessen common symptoms of “long COVID.”
GSK Shares Promising Results From Respiratory Syncytial Virus Vaccine Trial
Ahead of the IDWeek 2022 conference, GSK shared data from their phase 3 RSV vaccine trial.
Historical Perspective: Lessons from SARS-CoV-1
Before the emergence of COVID-19, this precursor virus was a global concern.
The Top Infectious Disease Stories This Week
Articles covering respiratory infections were our most-clicked this week.
Increase in Enteroviruses Seen with Decreases in COVID-19 Precautions
The Centers for Disease Control and Prevention (CDC) reports the rise in pediatric acute respiratory illnesses especially as there is a decrease in hygiene measures that were previously employed during the pandemic.
Quadrivalent Influenza Vaccine Safe and Effective for Children 6 Months-5 Years Old
Pediatric populations are disproportionately affected by influenza. The first cell-based quadrivalent flu vaccine offers potential for greater vaccine effectiveness.
FDA Approves Whooping Cough Vaccine
The vaccine is meant to be administered during the third trimester of pregnancy to the expecting mother to prevent this respiratory disease in infants younger than 2 months of age.
This Week's Most-Clicked Infectious Disease Stories
These were our most popular articles this week. Catch up with these trending infectious disease stories.
Improving Tuberculosis Prevention Programs Aimed at HIV Patients
The intervention included meeting with experts, texting services to improve and facilitate communication, and data collection and dissemination.
Health Officials Urge Flu Vaccination, But Few Adults Plan to Get the Shot
The CDC is urging all eligible persons to receive a flu shot, but a new survey shows fewer adults are planning to get the vaccine this season.
September's Top 5 Infectious Disease Stories
Catch up on Contagion's top stories from the month of September.
CDC Updates Pneumococcal Conjugate Vaccine Recommendations
The federal agency recommends using either PCV13 or PCV15 as part of a 4-dose series for pediatric patients between the ages of 2-59 months.
Is Eravacycline Ready for Prime Time Against CRAB Pneumonia?
Eravacycline is an antibiotic that has been touted for possible treatment of difficult-to-treat resistant (DTR) Gram-negative infections. But can it tackle carbapenem-resistant Acinetobacter baumannii (CRAB) infections?
Enterovirus D68 and Acute Flaccid Myelitis: What’s Known and Unknown
Why do some children develop polio-like paralysis after contracting enterovirus? Here’s everything we know about the rare but increasing reports of acute flaccid myelitis.
Rebound of COVID-19 After Treatment With Paxlovid
COVID-19 viral load rebound occurred in 2.3% of nirmatrelvir–ritonavir (Paxlovid) recipients and in 1.7% of placebo recipients.
Thromboembolism After COVID-19 vs. Influenza
A new study found that patients hospitalized with COVID-19 are at significantly higher risk for venous thromboembolism in the ensuing 3 months than are patients hospitalized with influenza.
FDA Plans to Approve Omicron-Targeting Booster Vaccines
Pfizer-BioNTech and Moderna have developed new booster shots optimized for Omicron. They could be approved as soon as Labor Day.
Pfizer Reports Positive Data on RSV Vaccine Candidate for Seniors
From its results, the company plans to file a Biologics License Application (BLA) with the FDA.
The Shrinking Incubation Period of COVID-19
The incubation period of the original, wild-type COVID-19 strain was 6.65 days, while the Omicron variant's incubation period has shortened to 3.42 days.
How Many People Contract Omicron Without Knowing?
56% of adults with evidence of Omicron seropositivity did not know they were infected.
Risk Factors for “Long COVID” in Children
More symptoms, older age, and longer hospitalization time increased the risk of post-COVID-19 conditions (long COVID) in children.
Tuberculosis Outbreak in US Traced to Bone Grafts
CDC links 2021 outbreak of tuberculosis in US affecting 113 persons and causing at least 3 deaths to bone grafts from one infected, deceased donor.
CDC Issues Health Advisory for Parechovirus in Infants
The CDC is advising clinicians to test for parechovirus in infants exhibiting fever, sepsis-like syndrome, or signs of neurological impairment.
Prior Infection Does Not Protect Children Against Omicron
Children and adolescents previously infected with COVID-19 or MIS-C demonstrated insufficient antibody titers and neutralization capability against the Omicron variant.
After Mild Infection, Children Retain Long-Term COVID-19 Immunity
At 12 months after COVID-19 infection, anti-SARS-CoV-2 spike receptor-binding domain IgG persisted in all age groups.
Investigational Vaccine Meets RSV Inoculation Challenge
Investigational vaccine demonstrates efficacy against respiratory syncytial virus in trial with adults inoculated with active RSV.
Even if Previously Infected, a COVID-19 Booster Vaccine Is Essential
Antibody levels decline in individuals with hybrid immunity similarly to vaccinated individuals, meaning all people need a booster vaccine to protect against future, potentially severe, infection.
All-Cause Maternal Mortality Before vs During COVID-19 Pandemic
Maternal mortalities increased 33.3% during the COVID-19 pandemic, while overall deaths increased 22%. Excess deaths were most prevalent in Hispanic and Black mothers.
Why Aren't People With COVID-19 Symptoms Getting Tested?
Many people who self-report as symptomatic for COVID-19 neglect to get tested, largely citing not knowing where to go for a test as the reason.
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