Kenneth Bender, PharmD, MA

Less ACE2 in nasal epithelium in children could present barrier to SARS-CoV-2 and explain the lower observed rate of pediatric infections.

Adding thromboelastogram to D-dimer measure could enable early ID of patients who require aggressive anticoagulation for severe COVID-19.

Two patient case series suggest pronation could improve oxygenation with non-invasive ventilation in some patients with coronavirus.

A risk score that predicts critical illness in patients hospitalized with COVID-19 could help inform allocation of clinical resources.

A series of essays consider the privileges and ethics of an immunity-based "passport" to proceed with fewer restrictions in the age of COVID-19.

Medical journal editors call for managed expectations for the numerous clinical trials that will soon release results on potential COVID-19 treatments.

Reduced T cell count in patients with coronavirus could be as important an indicator for urgent intervention as reduced respiratory function.

Even after putting public health policies in place, the state reached 2600 nursing home cases before the end of April.

Half of surveyed hospitals have no ventilator triage policies, and existing policies differ substantially and often lack guidance on implementation.

New expert recommendations follow from evidence showing the virus is a thrombo-inflammatory process that can affect multiple organs in addition to the lungs.

A hospital case series of patients with both COVID-19 and HIV describes recovery, but highlights the need to refine treatment.

An immune system defense that ensnares pathogens in neutrophil extracellular traps (NETs) could underlie severe respiratory distress, thrombosis in COVID-19.

Investigators assure that effective treatment of COVID-19 can be found without losing scientific integrity and public confidence.

Germany's National Academy of Sciences issued statements in March and April detailing necessary containment measures and a path to normalization.

A modelling study to forecast COVID-19 spread in China and inform decisions on relaxing restrictions, predicts a second wave that could require greater restrictions.

Its not only shortage of ventilators, but of the sedatives, anesthetics and paralytic agents for patients on ventilators that reveal inadequacies in supply chain.

Although controlled trial results of remdesivir for COVID-19 won't be available for several weeks, early experience with compassionate use is detailed in a new NEJM report.

Loss of smell or taste has been reported to occur with COVID-19 in absence of other symptoms, heightening risk of exposure for unknowing contacts.

Medical sleuths identify potential of baricitinib for COVID-19 by using artificial intelligence to sift through available agents that act on receptors of interest.

Anthony Fauci, MD, of NIAID, Robert Redfield, MD, of CDC, and others considered initial epidemiology from Wuhan China, and the need to obtain, and act on new data.

Ocular exams in a series of patients hospitalized with COVID-19 revealed one-third had conjunctivitis symptoms.

A placebo-controlled trial of hydroxychloroquine in patients hospitalized with COVID-19 finds the drug shortened time to recovery, possibly lessened severity.

The coronavirus pandemic is disrupting clinical trials for multiple diseases, from Alzheimer's to Zika.

New guidelines on COVID-19 from WHO, CDC, and CMS advise long-term care facilities on protecting their elderly, vulnerable populations and staff.

Clinicians are calling for greater preparedness for post acute care of patients who recover from COVID-19

Statistical models forecast the spread of COVID-19 based on pre-pandemic travel from Wuhan, China.

High-dose intravenous immunoglobulin appeared to reverse deteriorating courses of COVID-19 in 3 case reports from Wuhan, China.

Investigations in the US and China make a case for using convalescent plasma, a “last resort” for SARS, as an early treatment for COVID-19.

A Central Science report from the CAS division of the American Chemical Society details developments and recommends directions against COVID-19 pandemic.

New analyses of the novel coronavirus and previously circulating SARS viruses reveal promising immunologic targets for vaccine against COVID-19.