Coronavirus / COVID

Unpublished, interim phase 3 data show an approximate 50% reduction in hospitalizations and deaths versus placebo. Merck is expediting FDA application for the antiviral drug.

In the primary efficacy analysis, the risk of developing symptomatic COVID 19 was reduced by 77% with AZD7442.

The study author of the late-breaking IDWeek findings discusses what the new data mean for using the antiviral to reduce COVID-19 burden.

An expert explains the science of vaccine- and infection-induced immunity, and how it informs the timeline of COVID-19 outbreaks this year.

In newly hospitalized hypoxic patients with COVID-19, the monoclonal antibody significantly improved survival without invasive mechanical ventilation compared with placebo and available treatments, according to phase 3 trial results.

A new study breaks down the risk prediction of death or hospitalization related to COVID-19 in adults following their vaccination.

“Compared to the pre-COVID period, the odds ratio for CVD encounters was nearly doubled in each post-COVID period from 31 to 90 days post onset,” Brian Agan, MD, deputy science director and HIV research director of the Infectious Disease Clinical Research Program at USU/HJF and presenting author, told Contagion®.

Research suggests studies should adjust their cohort comparison group to account for demographics most represented by people living with HIV.

The companies will be seeking emergency authorization for a lighter-dose mRNA vaccine for children aged 5 to <12 years old.

Data finds low risk for anaphylaxis, myocarditis, and other potential complications.

Extended findings from blinded mRNA-1273 vaccine pivotal trial include efficacy across subgroups, including elderly and with coexisting conditions.

Only about 60% of Americans have immunity, a number too low to protect the country through “herd immunity,” according to a new report.

A CDC examination of a Delta outbreak in a Texas prison showed unvaccinated persons have higher attack rates, hospitalizations, and deaths, but vaccinated persons can still contract and spread the virus.

In a departure from the independent APIC advisors, CDC Director Rochelle Walensky, MD, has decided to recommend boosters for people in high-risk occupations.

The Advisory Committee on Immunization Practices posed a series of 4 questions related to a potential third shot of the Pfizer-BioNTech COVID-19 vaccine in various populations.

A third dose booster vaccination given to persons 60 years of age or over in Israel was confirmed to lower their rate of COVID-19 infection compared to a 2-dose regimen.

New research shows COVID-19 mortality risk to be more nuanced than previous studies.

The federal agency will grant an Emergency Use Authorization (EUA) for the third dose for seniors, those deemed high risk, and those with jobs that put them at risk of infection.

A presentation of available third-dose data suggest the adverse event rate is consistent with that observed with second doses.

Patients with cancer now have official confirmation that vaccinating against COVID-19 will protect them from contracting the virus.

With the Delta cases surging in recent weeks, and the upcoming flu season almost upon us, here is a glimpse of what providers and the public can expect when both viruses are circulating.

After two doses of the Pfizer-BioNTech COVID-19 vaccine, 83% of allogeneic hematopoietic stem cell transplant recipients showed positive antibody response.

Preprint data from a real-world evidence assessment, as well as preliminary reports from a 2-dose trial, support the company's pursuit for FDA authorization of a second COVID-19 vaccine dose.

The data, which reflects pre-pandemic routine vaccination levels, showed human papillomavirus vaccine rates increased among teens ages 13-17.

A smaller dosage was used and with their results the two companies plan to submit their data to governmental regulatory agencies around the world.

The Centers for Disease Control and Prevention's (CDC) VISION Network of health care systems provided data for test-negative design analysis of vaccine effectiveness in preventing COVID-19 acute admissions.

After voting against recommendation of a booster dose for people 16 years and older, the committee created a new question to vote on an EUA for a booster dose for people 65 years and older and those at high risk of COVID-19. They voted 18-0 in favor.

The VRBPAC voted 16-2 on Friday afternoon on the question they were presented.

A new study addressed the clinical outcomes in young adults who were hospitalized with COVID-19 across the United States.

A Food and Drug Administration (FDA) committee will discuss this topic as it pertains to the potential approval of a third dose of the Pfizer-BioNTech COVID-19 vaccine. The results of this meeting could have ramifications for the Biden Administration’s COVID-19 health policy.