Healthcare Associated Infections (HAI)

If the FDA approves maribavir, it will be the first and only treatment for adults with CMV as a result of a hematopoietic stem cell transplant or solid organ transplant.

A global study of C. difficile isolates worldwide found a very high prevalence of the bacteria on shoe soles.

Strong public health measures coupled with infection control practices can contain the spread of Candida auris.

Infection preventionists at UCLA used active surveillance screening and technology to take a proactive approach to staving off any potential outbreaks of the emerging fungal infection in their health system.

An emergency department in Canada saw a steep drop in emergency department visits and a spike in the proportion of serious bacterial infections among newborns and young infants during the first year of the pandemic, a new study found.

A study looked at the prevalence of Metallo-B-lactamase (MBLs) producing A. baumannii isolates in one hospital setting.

Sensors provided data for more hand washing opportunities for healthcare workers and affected related behaviors.

New ASM data show indoor environments are associated with quick and frequent pathogen contamination of the common respiratory device.

Examining pharmacological management in COVID-19 patients with ARDS requiring antifungal therapy during extracorporeal life support.

Study finds communicating on Electronic Medical Record (EMR) led to follow-up with infectious disease providers.

Machine learning improves prediction of bacterial sepsis among immunocompromised recipients of stem cell transplant.

Investigational therapy, ibrexafungerp, from Scynexis is being studied for fungal infections and is moving closer towards a goal of FDA approval later this year.

Implications for antimicrobial use and antimicrobial resistance.

A £100 million donation from Ineos will fund collaborative effort across sciences.

In a mature market of agents, the investigational therapy, ibrexafungerp, from Scynexis is looking at a few antifungal indications with a potential FDA approval in 2021.

More than 13 million children did not receive their first DTP vaccine dose in 2019—and investigators anticipate the 2020 rate will be worse.

New data may evidence oral care as a therapeutic measure to reduce bacterial and viral spread.

New data show ADA-recommended oral care for inpatients is associated with an 85% reduction in NVHAP infections at an 800-bed medical center over a year.

Cefiderocol was noninferior to high-dose, extended-infusion meropenem in terms of all-case mortality in patients with gram-negative nosocomial pneumonia and showed similar clinical and microbiological efficacy to best available therapies in carbapenem-resistant, gram-negative bacterial infections, according to 2 recently released studies.

Expansion of antimicrobial stewardship strategies to include vertical methods represents an opportunity for programs, both new and established, to further optimize antimicrobial use.

Candida auris is an emerging health care–associated multidrug-resistant fungal pathogen with public health concerns more similar to those of extensively drug-resistant bacterial pathogens than other species of Candida.

The antibacterial is efficacious in a majority of patients in a small study.

Hollis O’Neal, MD, the national primary investigator for the Cytovale early sepsis detection system, discusses sepsis and COVID-19 and provides an overview of his pilot study.

Community-acquired infections—including those associated with outpatient settings—are still problematic, authors say.