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The greatest risk factors for recurrent Clostridioides difficile infection (CDI) were age of at least 65 years, severe primary CDI, and use of non-CDI antibiotics. Patients with these risk factors should be prioritized for bezlotoxumab therapy.

Identifying High-Risk Recurrent Clostridioides Difficile Patients for Bezlotoxumab

Selecting initial antibiotic for ventilator-associated pneumonia from Gram staining and resistance records could reduce broad spectrum agents.

Initiating Antibiotic for Severe Pneumonia from Gram Staining Could Reduce Broad Spectrum Agents 

A recent study showed that 25% of mattresses within 4 hospitals required complete replacement, underlying a serious health risk that could lead to unnecessary infections. 

The HealthCare-Associated Infection Risk Hiding in Plain Sight

A new report based on samples from Texas and Kenya found significant proportions of samples from patients with CDI had nonsusceptible isolates.

Vancomycin Nonsusceptibility Common in CDI Cases

For the first time, a research team mapped C difficile’s outer “S-layer,” finding the dangerous bacteria’s chainmail-like shell enables it to be highly resistant.

New Visual of C Difficile Armor Explains its Resilience 

To reduce antimicrobial resistant pathogens, nursing homes should carefully monitor their use of hospital-grade antibiotics.

Nursing Homes at Increased Risk of Antibiotic Resistant Infections

Hospitals with lower c difficile antibiotic usage averaged shorter length-of-stay than hospitals that prescribed more antibiotics.

Hospitals That Use More Antibiotics Have More C Difficile Infections

A predictive tool, POC Advisor, has been developed to support faster diagnosis and intervention of this dangerous condition. 

Detecting Sepsis Earlier

Implementation of  CMS Severe Sepsis and Septic Shock Management Bundle did not reduce mortality rates in study of 114 hospitals.

Adhering to Standard for Sepsis Treatment Did Not Reduce Mortality

Ferring’s Microbiome Health Index is a diagnostic tool that may help distinguish a healthy gut microbiome from post-antibiotic dysbiosis, and could potentially identify debilitating illnesses such as C difficile infection


HEALTHCARE-ASSOCIATED INFECTIONS (HAI)

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