Risk-Set Matching Cuts Bias in Estimating Effects of Hospital-Acquired Infections
Studies that do not consider time of infection may overestimate the impact of hospital-acquired infections on patient outcomes, according to the results of a new study.
De-Escalation in Under 48 Hours Reduces 90-Day C difficile Infection Incidence 3-Fold
A novel study from Seddon and colleagues adds to the body of evidence that supports what antimicrobial stewardship programs are so often challenged to do, early de-escalation.
Reinforcing Infection Prevention in the Operating Room Anesthesia Work Area: New SHEA Guidelines
SHEA released new guidance to help increase infection control in the operating room.
Carriage of ESBL-PE May Increase the Risk of Colorectal Surgical Site Infections
Is it time to screen for these bacteria and modify colorectal surgical prophylaxis?
Exploring Primary Prophylaxis for Invasive Pulmonary Aspergillosis
Invasive aspergillosis affects up to 13% of immunocompromised patients who are in the hospital.
Plazomicin Immunoassay Cleared by The Center for Devices and Radiological Health
The Center for Devices and Radiological Health of the US FDA has issued clearance for the Thermo Scientific QMS Plazomicin Immunoassay.
Fighting Operating Room Staphylococcus aureus Transmission—What Are We Missing?
A new study sheds light on sources of Staphylococcus aureus transmission in the operating room.
Decontaminants Don't Cut Bloodstream Infection Risk in Ventilated ICU Patients
Although decontamination strategies are thought to generally slash the rate of infection in ICUs, a new study finds that the use oral and digestive tract decontaminants in ventilated ICU patients is not associated with a reduction in antibiotic-resistant bloodstream infections.
Analyses Support Rezafungin for Prevention of Aspergilosis Following Bone Marrow Transplant
Pharmacokinetic analyses provide evidence to support once-weekly dosing of rezafungin to prevent Aspergillus fumigatus in bone marrow transplant recipients.
Antimicrobial Stewardship Programs: Are They Pulling ID Physicians Away from Infection Prevention Programs?
Are we investing in infection prevention programs like we should or are competing interests pulling resources?
Update on Candida auris: Statistics, Detection, and a Phase 2 Trial
As of October 31, 2018, the CDC has reported 457 clinical cases of confirmed C auris infection with a majority in New York (>50%), New Jersey, and Illinois.
Bezlotoxumab More Effective in Patients with High Risk for C Diff Recurrence
Secondary analyses indicate that bezlotoxumab is more effective in reducing C diff recurrence in patients with pre-specified risk factors.
Stethoscope Disinfecting—We're Just Not Doing It
A new study finds that despite CDC standards, stethoscopes aren't being disinfected.
The Red Box—An Infection Control Strategy to Increase Communication?
A new study evaluated the use of red boxes in patient rooms to help encourage patient care while in isolation.
Piperacillin-Tazobactam Very Disruptive to Gut Flora
Additionally, its use is associated with colonization of the gastrointestinal tract by lower relative quantities of some potentially protective bacterial organisms.
Short-Term Use of Gentamicin Does Not Harm Kidneys, Study Finds
New research finds it is safe to use gentamicin to treat bacteremia, provided it is used for a short term and only given once per day.
The Efficacy of Fecal Transplants for C diff
Sahil Khanna, MBBS, MS, discusses the efficacy of fecal transplants and new investigational candidates that are being evaluated in clinical trials.
Rapid Molecular Diagnostics for C diff and Sepsis
Maureen Spencer, RN, M.Ed., discusses how rapid molecular diagnostics are changing the treatment timeline for sepsis and Clostridium difficile (C diff).
WHO Reports on Global Antibiotic Consumption
The latest report from WHO highlights trends in antimicrobial consumption and use across the world, underscoring the need for international antimicrobial stewardship programs.
Sepsis and Antimicrobial Resistance Awareness Gain Ground, But Action Must Continue
As antimicrobial therapies become less effective, more people are at risk for infections that can progress to sepsis.
Prosthetic Joint Infection: Type of Surgery Influences Outcome
A new study reveals that the type of surgery performed to treat these infections plays a more significant role in outcomes than other factors.
The Contingent Valuation of C Diff Antibiotics
Glenn Tillotson, PhD discusses the development of new antibiotics and therapies for C diff during an era when antibiotic resistance is a serious global health threat.
C Difficile Infection Is Associated With Higher Mortality Rates in Patients With Cirrhosis
Clostridium difficile infection leads to higher rates of overall mortality among patients with cirrhosis compared to those who do not, according to a new study.
Lessons From the MERINO Trial
Is the use of piperacillin/tazobactam for bacteremia caused by ceftriaxone-nonsusceptible Escherichia coli and Klebsiella pneumoniae an obsolete practice?
Addressing Shortcomings in Infection and Sepsis Treatment Should Be Top of the Priority List
As clinicians and health care executives work to strike a balance between reducing costs and improving clinical outcomes, the importance of sepsis identification and treatment cannot be underscored enough, and starts with evaluating current practices for infection management.
Improving Hospital Disinfection to Prevent C Diff
Edmund A. Hooker, MD, DrPH, discussed the gaps in disinfection in the hospital and how hospital beds can be properly sanitized to prevent the spread healthcare-associatedted infections.
Study Identifies Risk Factors for Vascular Graft Infections
Vascular graft infections are serious complications of reconstructive vascular surgery that may increase patients’ morbidity and mortality.
Finally, Some Good News on Health Care-Associated Infections: Public Health Watch
C diff and pneumonia still pose significant threats, according to the hospital survey.
Mount Sinai Investigators Developing a Novel Nanotechnology-Based Organ Acceptance Therapy
A new study on a novel experimental nanotechnology-based organ transplant acceptance therapy offers hope for reduced organ rejection without immune suppression.
Fluoroquinolone Antibiotics: More Recommendations for Prudent Use
Despite concerning findings and warnings, fluoroquinolones have remained one of the world’s most commonly prescribed antibiotic classes, with the United States accounting for more than 32 million prescriptions in 2015 alone.
2 Clarke Drive Cranbury, NJ 08512