Antibiotics

Empiric use of fluoroquinolones looks to be an alternate option for the treatment of gram-negative bloodstream infections when risk factors for antimicrobial resistance are not present.

A lack of coordination among regulating bodies, pharma manufacturers, standard development organizations, and laboratory testing device companies has muddied efforts to stop antibiotic resistance; the 21st Century Cures Act aims to fix that.

Increased stewardship may reduce administration of drugs to low birth-weight babies designed to prevent early-onset sepsis.

Stay up-to-date on the latest infectious disease news by checking out our top 5 articles of the week.

Bruce A. Mueller, PharmD, explains the risk factors for augmented renal clearance.

Nabriva Therapeutics plans to file a New Drug Application with the FDA in the fourth quarter of 2018.

Bruce A. Mueller, PharmD, shares some of the pharmacokinetic alterations that occur in patients who are in acute kidney failure in the intensive care unit.

Comparing 2 commonly prescribed treatments for urinary tract infections, an international team of researchers discovers that 1 is clearly superior.

Kenneth P. Klinker, PharmD, and Jason M. Pogue, PharmD, share some strategies to address beta-lactam dosing issues that they employ at their institutions.

Edward J. Septimus, MD, explains how smaller hospitals can overcome the challenges that come with having fewer resources to implement a robust antibiotic stewardship program.

The drug met its primary endpoint of noninferiority to vancomycin at both 48 to 72 hours after drug initiation and test of cure.

Jason M. Pogue, PharmD, discusses the challenges clinicians face when dosing beta-lactams based on the current guidelines.

In case you missed them, we’ve compiled a list of the latest recalls posted this week.

Bruce A. Mueller, PharmD, shares how clinicians in the inpatient setting can quantify acute kidney injury in adults on antibiotics.

A new study shows the benefits of widespread antibiotic distribution, but what about concerns about encouraging antibiotic resistance?

A study shows that pharmacist-driven education and encouragement of antibiotic self-stewardship can decrease the duration of therapy for broad-spectrum antibiotics.

A new literature review offers a summary of the latest research into uncomplicated bacteremia.

New software unveiled last month suggests hospitals could make patient-specific predictions of antibiotic susceptibility.

The rise in antibiotic resistance has led experts to focus on how to appropriately manage and regulate shared-use antibiotics in humans and animals.

Julia E. Szymczak, PhD, shares the results of her study which revealed that fear drives some clinicians to prescribe inappropriately.

This emotional drive carried throughout the continuum of the prescribing pathway, from initial prescription to stopping or de-escalating antibiotics.

Investigational beta-lacatamase inhibitor IMI/REL demonstrates a favorable overall response against certain imipenem-non-susceptible bacterial infections.

Researchers present positive new data from multiple studies of VIBATIV at the 2018 ECCMID conference in Madrid, Spain.

Expert panelists in the field of infectious diseases discuss the growing threat of antimicrobial resistance.

According to recent research from Johns Hopkins Medicine, when it comes to making choices on appropriate antibiotic prescribing, outpatient providers are making the decision based on patient demand, not necessarily on what's actually appropriate for the condition.