Vaccines

Investigators in the first human trial of a MERS-CoV candidate report strong immune responses and no serious adverse events, advancing the vaccine candidate to phase 1/2a and phase 2 trials.

An update for clinical providers.

The Ad26.ZEBOV, MVA-BN-Filo vaccine regimen will be evaluated in an open-label, single-arm study of 800 participants, including frontline health care workers.

The first step (prime) is to immunize with conventional vaccines through a needle in the arm. The second step (pull), is to apply an antibiotic cream that helps attract, T cells, to the site of virus growth.

The latest guidance on preparing for and responding to measles in your health care facility.

When speaking with patients or parents, it is important for health care practitioners to stress that vaccines are safe, and vaccines save lives.

The adjusted hazard ratios for 1-dose and 2-dose recipients were comparable to the 3-dose recipients (1 dose 1.01 [95%CI 0.81–1.26], 2 doses 1.00 [0.85–1.17]) after adjusting for age at vaccination among the vaccinated group.

The phase 2a study compares a bivalent combination of Clade C and Mosaic gp140 with a single-valent Clade C gp140.

Several states have or are considering laws that would circumvent consent from anti-vax parents.

Mosaico plans to register 3800 HIV-negative participants aged 18 to 60 years when enrollment opens later this year.

Following the elimination of personal belief exemptions, the statewide rate of kindergartners without up-to-date status for required vaccinations decreased from 9.84% in 2013 to 4.87% in 2017.

ACIP voted 10-to-4 to expand the recommended HPV vaccine “catch-up” age for men from 21 to 26, matching the existing guidelines for women.

Diversity of Group A Streptococcus strains has frustrated vaccine development efforts, but investigators have taken a step closer to finding a common gene signature in nearly all strains.

International travel and poor vaccine uptake are among the key factors identified by investigators who mapped counties at-risk for measles cases in the United States.

Following a rise in sexually transmitted infection diagnoses in recent years, NIAID is awarding grants for research into syphilis, gonorrhea, and chlamydia vaccine candidates.

The rate of health care-associated influenza cases per season decreased from a median of 16.8 cases pre-policy rollout to 5.2 cases post-policy rollout at a large pediatric hospital.

An Italian study found that immunization rates are high among health workers, but an important proportion of employees are not immune to mumps.

Contagion® caught up with William Schaffner, MD, medical director of the National Foundation for Infectious Diseases, to discuss the highlights from this week’s NFID Annual Conference on Vaccinology Research.

An intradermal Ebola vaccine candidate shows promise as a safe, temperature-stable, and effective option for preventing outbreaks, new data show.

The latest case cluster in the United States has led a university to change policy regarding the MMR vaccine.

To shed light on the current measles outbreaks, Contagion® is launching a video series featuring the perspectives of 2 medical experts.