Zoonotic & Vector-Borne Diseases

Focus group-based study reveals challenges in travel medicine among US-based visitors to the region.

The FDA has approved the launch of the first in-human clinical trial evaluating the efficacy of a new synthetic DNA-encoded monoclonal antibody (DMAb) therapy to prevent Zika virus infection.

At Day 28, 100% seroconversion rate was achieved in a pooled analysis of all participants who received a single vaccination of VLA1553.

Investigators have identified and characterized Mengla virus, a filovirus that is genetically distinct from Ebola and Marburg viruses.

Despite the increase of live poultry-related Salmonella outbreaks, environmental sampling at hatcheries is not routinely conducted leaving the outbreak source unknown.

Investigators have identified Marburg virus in Sierra Leone bats, marking the first time the hemorrhagic fever has been discovered in West Africa.

Expanding the differential for diarrhea beyond Clostridium difficile.

While most infants exposed to Zika in utero show no severe developmental defects, a new study offers an estimate of the impact of Zika-associated impairment within the first 2 years of life.

A study found that the climate of the eastern area of the United States is similar to the native habitat of the Asian longhorned tick in Asia and Australia, which suggests the tick will become more common in the US.

University of Hawaii medical school investigators have developed a Zika virus vaccine candidate that is proving effective in preclinical trials.

The results of a new Dutch study suggest a rationing protocol does not diminish the effectiveness of the vaccine.

Little is known about the ecology and biology of the dangerous tick that the CDC has labeled an emerging disease threat to both humans and animals.

This often-ignored zoonotic disease may be a rising problem around the world.

Through retrospective analysis, investigators have identified a second case of rat hepatitis E virus in a human, which has close genetic relation to the first case.

The disease is now widespread among rodents in New Orleans, posing an increased public health risk of rat lungworm disease to people in the area.

Two new studies highlight how antibodies from prior infection with Zika or Dengue may increase the severity of illness in the other, impacting the infants of pregnant women who are infected.

A new study examining cytokines in the blood of pregnant women infected with Zika may help investigators create a screening test for early detection of fetal abnormalities from the virus.

Highest amounts of Toxocara egg contamination were in areas that could contain food droppings or animal waste.

Sanofi Pasteur’s dengue vaccine (Dengvaxia) is moving one step closer to being approved in the United States as the FDA just accepted a Biologics License Application for the vaccine.

The proliferation of malaria-specific cord blood CD4+ T cells is associated with protection from childhood malaria.

This case report is the fourth documented case of Lyme-induced syndrome of inappro­priate secretion of antidiuretic hormone (SIADH).

The virus may be fading from mainstream headlines, but it is active and physicians must stay vigilant.

From August 2014 to September 2018, the CDC received information on a total of 386 confirmed US cases of a polio-like illness occurring mostly among children.

The inactivated recombinant vaccine protected guinea pigs that were exposed to the Lassa virus 58 days post-vaccination.

New report highlights potential for direct testing of the tick-borne disease.

The Government of India Ministry of Health and Family Welfare has announced 22 confirmed cases of Zika virus in Jaipur as of October 8, 2018.

Kenneth E. Sherman, MD discusses the zoonotic hepatitis E virus and about the first reported case of rat-to-human transmission.

Los Angeles County Department of Public Health is investigating an influx of cases of flea-borne typhus in downtown Los Angeles.

The new vaccine schedule is 7 days between doses for adults aged 18 to 65, instead of the standard 28 days.

In September 2017, a patient in Hong Kong was diagnosed with rat hepatitis E virus after inflammation of the liver was observed.